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帕金森病中的遗传性下颌震颤。

Hereditary chin tremor in Parkinson's disease.

作者信息

Erer Sevda, Jankovic Joseph

机构信息

Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas, USA.

出版信息

Clin Neurol Neurosurg. 2007 Nov;109(9):784-5. doi: 10.1016/j.clineuro.2007.05.020. Epub 2007 Jul 6.

Abstract

Hereditary chin tremor (HCT) is characterized by rhythmical, involuntary movements of the chin muscles usually inherited in an autosomal dominant pattern. We describe a 74-year old man with familial, childhood-onset chin tremor, and a 3-year history of progressive hand tremor, gait difficulty, and other parkinsonian features. Since chin tremor often occurs in Parkinson's disease (PD), a coexistent HCT may not be recognized unless past and family history of tremor is carefully explored.

摘要

遗传性颏部震颤(HCT)的特征是颏部肌肉有节奏的、不自主运动,通常呈常染色体显性模式遗传。我们描述了一名74岁男性,有家族性儿童期起病的颏部震颤,并有3年进行性手部震颤、步态障碍及其他帕金森病特征的病史。由于颏部震颤常发生于帕金森病(PD),除非仔细探究震颤的既往史和家族史,否则可能无法识别并存的HCT。

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