慢性丙型肝炎病毒感染与蚕食性角膜溃疡无关。
Chronic hepatitis C virus infection is not associated with Mooren's ulcer.
作者信息
Wang Q-S, Yuan J, Zhou S-Y, Chen J-Q
机构信息
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
出版信息
Eye (Lond). 2008 May;22(5):697-700. doi: 10.1038/sj.eye.6702788. Epub 2007 Jul 6.
AIM
To investigate the association between chronic hepatitis C virus (HCV) infection and Mooren's ulcer.
METHODS
Eight patients from different parts of China who were diagnosed with Mooren's ulcer at the Zhongshan Ophthalmic Center, Guangzhou (China) were screened for chronic HCV infection. Mooren's ulcer was diagnosed by the typical ulcer morphology, detailed case history, physical examination, and comprehensive laboratory tests. All patients had serological screening for HCV infection.
RESULTS
Six male and two female patients were enrolled in the study. Their ages ranged from 31 to 65 years (mean 43.6+/-13.7). None of them was reported to have any clinical evidence of chronic HCV infection before enrolment and all were negative for HCV serology.
CONCLUSION
There was no association between chronic HCV infection and Mooren's ulcer in this limited case series study.
目的
探讨慢性丙型肝炎病毒（HCV）感染与蚕蚀性角膜溃疡之间的关联。
方法
对在中国广州中山眼科中心被诊断为蚕蚀性角膜溃疡的8名来自中国不同地区的患者进行慢性HCV感染筛查。通过典型的溃疡形态、详细的病史、体格检查和综合实验室检查来诊断蚕蚀性角膜溃疡。所有患者均接受HCV感染的血清学筛查。
结果
6名男性和2名女性患者纳入研究。他们的年龄在31至65岁之间（平均43.6±13.7）。在入组前，均未报告有任何慢性HCV感染的临床证据，且所有患者的HCV血清学检查均为阴性。
结论
在这个有限的病例系列研究中，慢性HCV感染与蚕蚀性角膜溃疡之间没有关联。
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