尿道阻力压力与最大尿道闭合压力及压力性尿失禁的相关性
The correlation of urethral resistance pressure with maximum urethral closure pressure and stress incontinence.
作者信息
Kuhn Annette, Kuhn Peter, Dreher Ekkehard
机构信息
Department of Urogynaecology, Frauenklinik, Inselspital Bern, Switzerland.
出版信息
Eur J Obstet Gynecol Reprod Biol. 2008 Jan;136(1):116-20. doi: 10.1016/j.ejogrb.2007.04.002. Epub 2007 Jul 5.
OBJECTIVE
Aim of the study was to correlate urethral retro resistance pressure with the maximum urethral closure pressure (MUCP) and functional urethral length (FUL) in patients with urinary incontinence and healthy individuals.
STUDY DESIGN
Two hundred and twenty patients with the complaint of urinary incontinence had a urodynamic examination including urethral pressure profiles and URP. Additionally, 15 healthy individuals without the complaint of any incontinence had their URP and urethral pressure profiles measured. The correlation of MUCP, FUL and URP were calculated using Graph Pad Instat 4.0 for windows.
RESULTS
URP correlates well with the diagnosis of urodynamic stress incontinence. Correlation coefficient between URP and MUCP is 0.9262. Healthy individuals have significantly higher values for URP and MUCP.
CONCLUSION
URP is a valuable less invasive test than conventional urethral function tests for the diagnosis of urodynamic incontinence with an excellent correlation of MUCP and URP.
目的
本研究旨在探讨尿失禁患者及健康个体的尿道逆行阻力压力与最大尿道闭合压（MUCP）及功能性尿道长度（FUL）之间的相关性。
研究设计
220例有尿失禁主诉的患者接受了包括尿道压力描记和尿道逆行阻力压力（URP）测定在内的尿动力学检查。另外，15例无任何失禁主诉的健康个体也进行了URP和尿道压力描记测定。使用适用于Windows系统的Graph Pad Instat 4.0软件计算MUCP、FUL与URP之间的相关性。
结果
URP与尿动力学压力性尿失禁的诊断密切相关。URP与MUCP之间的相关系数为0.9262。健康个体的URP和MUCP值显著更高。
结论
对于尿动力学性尿失禁的诊断，URP是一种比传统尿道功能检查侵入性更小的有价值的检查，且MUCP与URP之间具有良好的相关性。
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