Masuda H, Yamada T, Nagamatsu H, Nagahama K, Kawakami S, Watanabe T, Negishi T
Department of Urology, Kasukabe Municipal Hospital.
Hinyokika Kiyo. 1994 Mar;40(3):209-13.
The urethral pressure profile (UPP) at rest and under stress was recorded by means of double lumen microtip transducer catheter in 58 females with stress urinary incontinence (SUI). The patients were divided into three groups including mild to moderate SUI patients (n = 29, group 1), severe SUI patients (n = 16, group 2) and very severe SUI patients (n = 13, group 3) according to a one-hour pad test. The functional urethral length (FUL) was divided into four equal lengths and the pressure transmission ratio (PTR) was calculated for each quartile for each female. We examined the correlation of the severity of SUI with urethral pressure parameters: maximum urethral closure pressure (MUCP) at rest and functional urethral length (FUL) at rest and PTR. SUI patients showed a negative association between the severity of SUI and MUCP, but no significant differences in the FUL were seen between the different groups. PTR was shown to be similar in order for all groups of SUI patients showing a linear decrease in the value of the PTR along the FUL. However, we found a negative association between the severity of SUI and PTR (P < 0.05) at the middle part of the FUL (Q3). These findings indicate that there are more defective distal sphincter mechanisms in severe SUI patients than in mild to moderate SUI patients. There was an overlap between the different groups in both MUCP and PTR at the middle urethra (Q3), suggesting that other parameters are related with the severity of SUI.
采用双腔微尖传感器导管记录了58例压力性尿失禁（SUI）女性患者静息和应激状态下的尿道压力分布图（UPP）。根据1小时的尿垫试验，将患者分为三组，包括轻度至中度SUI患者（n = 29，第1组）、重度SUI患者（n = 16，第2组）和极重度SUI患者（n = 13，第3组）。将功能性尿道长度（FUL）分为四个相等的长度，并计算每位女性每个四分位数的压力传递率（PTR）。我们研究了SUI严重程度与尿道压力参数之间的相关性：静息时的最大尿道闭合压（MUCP）、静息时的功能性尿道长度（FUL）和PTR。SUI患者中，SUI严重程度与MUCP呈负相关，但不同组之间的FUL未见显著差异。所有SUI患者组的PTR相似，显示PTR值沿FUL呈线性下降。然而，我们发现在FUL的中间部分（Q3），SUI严重程度与PTR呈负相关（P < 0.05）。这些发现表明，重度SUI患者比轻度至中度SUI患者存在更多远端括约肌机制缺陷。在尿道中部（Q3），不同组的MUCP和PTR存在重叠，提示其他参数与SUI的严重程度有关。
