Leiva-Santana C, Monge-Argilés J A, Galván-Berenguer B
Servicio de Neurología, Hospital General Universitario de Alicante, 03010, Alicante, Spain.
Rev Neurol. 2007;45(1):7-12.
The literature on Parkinson's disease (PD) has acknowledged the existence of certain characteristic features in the personality and moods of patients which could be caused by the disease or may be a consequence of the functional disability produced by the condition.
To compare the variables personality, depression, anxiety and cognitive functions between a group of patients with PD and a control group with a similar functional disability.
The study involved a sample made up of 55 patients with PD and 55 patients with rheumatologic or orthopaedic diseases, who were paired by age, sex and functional disability according to the Schwab and England scale. Personality tests (personality questionnaire for adults adapted to the Spanish population, sensation-seeking questionnaire, rigidity questionnaire, coping strategies questionnaire), Hamilton Depression Scale, State-Trait Anxiety Inventory and tests for cognitive functions (Minimental and Progressive Matrixes Test).
Patients with PD score significantly higher than control subjects on the Hamilton Depression Scale. No significant differences were found in any of the variables in the three personality tests that were used, on the anxiety scale or in the cognitive functioning tests.
No differential personality traits were found between our patients and the control subjects, which would therefore not support the existence of a characteristic personality in PD. Our patients with PD show more symptoms of depression than is to be expected in relation to their functional disability, and this could influence the results obtained by other authors in studies on this subject.
关于帕金森病(PD)的文献已经认识到患者的人格和情绪存在某些特征,这些特征可能由疾病引起,也可能是该病症导致的功能残疾的结果。
比较一组帕金森病患者和一组具有相似功能残疾的对照组之间的人格、抑郁、焦虑和认知功能变量。
该研究涉及一个样本,由55名帕金森病患者和55名患有风湿性或骨科疾病的患者组成,根据施瓦布和英格兰量表按年龄、性别和功能残疾进行配对。进行人格测试(适用于西班牙人群的成人人格问卷、感觉寻求问卷、僵化问卷、应对策略问卷)、汉密尔顿抑郁量表、状态-特质焦虑量表以及认知功能测试(简易精神状态检查表和渐进矩阵测试)。
帕金森病患者在汉密尔顿抑郁量表上的得分显著高于对照组。在所使用的三项人格测试的任何变量、焦虑量表或认知功能测试中均未发现显著差异。
在我们的患者和对照组之间未发现差异人格特质,因此不支持帕金森病存在特征性人格的观点。我们的帕金森病患者表现出的抑郁症状比根据其功能残疾预期的更多,这可能会影响其他作者在该主题研究中获得的结果。