Pinkerton Steven D, Benotsch Eric G, Mikytuck John
Medical College of Wisconsin, Wisconsin, USA.
Eval Rev. 2007 Aug;31(4):401-12. doi: 10.1177/0193841X07300237.
The "gold standard" for evaluating human immunodeficiency virus (HIV) prevention programs is a partner-by-partner sexual behavior assessment that elicits information about each sex partner and the activities engaged in with that partner. When collection of detailed partner-by-partner data is not feasible, aggregate data (e.g., total numbers of partners and acts of various types) must suffice. Lack of specificity in the primary data often translates into uncertainty in modeled outcomes, such as participants' risk of HIV acquisition. To our knowledge, no previous study has attempted to quantify this uncertainty. The results of the present analysis of the risk of HIV acquisition by men vacationing in Key West indicate that the use of aggregate rather than partner-by-partner data introduced relatively little uncertainty into the HIV risk estimates. Collection of aggregate data is a viable alternative to detailed partner-by-partner data, at least in some circumstances.
评估人类免疫缺陷病毒(HIV)预防项目的“金标准”是逐个性伴侣的性行为评估,该评估能获取每个性伴侣的信息以及与该伴侣进行的活动。当逐个性伴侣收集详细数据不可行时,汇总数据(例如,伴侣总数和各类行为的数量)必须足够。原始数据缺乏特异性往往会转化为模型结果的不确定性,例如参与者感染HIV的风险。据我们所知,之前没有研究试图量化这种不确定性。本次对在基韦斯特度假的男性感染HIV风险的分析结果表明,使用汇总数据而非逐个性伴侣的数据,在HIV风险估计中引入的不确定性相对较小。至少在某些情况下,收集汇总数据是详细逐个性伴侣数据的可行替代方案。