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儿童颈椎结核

Cervical spine tuberculosis in children.

作者信息

Govender S, Ramnarain A, Danaviah S

机构信息

Department of Orthopaedic Surgery, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, 719 Umbilo Road, Congella 4013, South Africa.

出版信息

Clin Orthop Relat Res. 2007 Jul;460:78-85. doi: 10.1097/BLO.0b013e31806a915f.

DOI:10.1097/BLO.0b013e31806a915f
PMID:17620809
Abstract

The presentation and outcome of pediatric cervical spine tuberculosis are different from those of adult cervical spine tuberculosis. We retrospectively reviewed the clinical and radiographic outcome of 58 children with cervical spine tuberculosis treated nonoperatively and operatively between 1996 and 2004. The mean age was 3.7 years (range, 1.9-14 years). The cervicodorsal junction was affected in 27 children, the atlantoaxial complex in 19 children, and the mid-cervical spine in 12 children. Multifocal noncontiguous spinal lesions were observed in 21 patients. Surgery was performed in 25 children for: neurologic deficit (14); drainage of retropharyngeal abscesses (four); atlantoaxial fusion for late C1-C2 instability (three); and progressive deformity and pain (four). Neurologic recovery occurred in all patients. Seven patients were lost to followup within 2 years. The minimum followup was 2.4 years (mean, 3.5 years; range, 2.4-10 years). We attributed the improved functional outcome after anti-TB chemotherapy alone to the remodeling potential of the pediatric cervical spine. Surgery was performed only for neurologic deficit, an atlantodental interval greater than 5 mm on flexion/extension view, and progressive deformity. Four patients developed superficial wound infection, two patients had graft repositioning for a slipped graft, and seven children developed a grade 1 pressure sore over the scalp while on traction.

摘要

小儿颈椎结核的表现及预后与成人颈椎结核不同。我们回顾性分析了1996年至2004年间58例接受非手术和手术治疗的小儿颈椎结核患者的临床及影像学预后。平均年龄为3.7岁(范围1.9 - 14岁)。27例患儿颈胸交界处受累,19例患儿寰枢椎复合体受累,12例患儿颈椎中段受累。21例患者观察到多灶性非连续性脊柱病变。25例患儿接受了手术治疗,原因如下:神经功能缺损(14例);咽后脓肿引流(4例);晚期C1 - C2不稳定行寰枢椎融合术(3例);进行性畸形和疼痛(4例)。所有患者神经功能均有恢复。7例患者在2年内失访。最短随访时间为2.4年(平均3.5年;范围2.4 - 10年)。我们将单纯抗结核化疗后功能预后的改善归因于小儿颈椎的重塑潜力。仅在出现神经功能缺损、屈伸位片上寰齿间距大于5 mm以及进行性畸形时才进行手术。4例患者发生浅表伤口感染,2例患者因移植物移位而行移植物重新定位,7例患儿在牵引期间头皮出现1级压疮。

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