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与年龄相关的睡眠依赖性记忆巩固能力下降。

Age-related decline of sleep-dependent consolidation.

作者信息

Spencer Rebecca M C, Gouw Arvin M, Ivry Richard B

机构信息

Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720-1650, USA.

出版信息

Learn Mem. 2007 Jul 10;14(7):480-4. doi: 10.1101/lm.569407. Print 2007 Jul.

Abstract

Sleep-dependent memory consolidation is observed following motor skill learning: Performance improvements are greater over a 12-h period containing sleep relative to an equivalent interval without sleep. Here we examined whether older adults exhibit sleep-dependent consolidation on a sequence learning task. Participants were trained on one of two sequence learning tasks. Performance was assessed after a 12-h break that included sleep and after a 12-h break that did not include sleep. Older and younger adults showed similar degrees of initial learning. However, performance of the older adults did not improve following sleep, providing evidence that sleep-dependent consolidation is diminished with age.

摘要

运动技能学习后可观察到睡眠依赖性记忆巩固

与不含睡眠的同等时长相比,在包含睡眠的12小时期间,表现提升更为显著。在此,我们研究了老年人在序列学习任务中是否表现出睡眠依赖性巩固。参与者接受了两项序列学习任务之一的训练。在包含睡眠的12小时休息后和不包含睡眠的12小时休息后对表现进行评估。老年人和年轻人表现出相似程度的初始学习。然而,老年人在睡眠后的表现并未改善,这证明睡眠依赖性巩固会随着年龄增长而减弱。

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