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肾脏疾病发病率和进展中的种族差异。

Racial differences in the incidence and progression of renal diseases.

作者信息

Smith S R, Svetkey L P, Dennis V W

出版信息

Kidney Int. 1991 Nov;40(5):815-22. doi: 10.1038/ki.1991.281.

DOI:10.1038/ki.1991.281
PMID:1762285
Abstract

There is an excess incidence of ESRD treatment among non-White North Americans that is not completely explained by the racial prevalences of the underlying diseases, including hypertension, which can potentially cause renal disease. The racial difference is particularly striking for presumed nephrosclerosis from hypertension and for nephropathy from Type II diabetes, but is not yet substantiated for ESRD attributed to polycystic kidney disease or Type I diabetes. The existing data are insufficient to support the notion that poorer blood pressure control alone is responsible for the racial differences in incident ESRD. Black race (and possibly Mexican or Native American heritage) may be a specific risk factor for ESRD, independent of hypertension and its treatment.

摘要

北美非白人中终末期肾病(ESRD)治疗的发病率过高,这不能完全用包括高血压(可能导致肾病)在内的基础疾病的种族患病率来解释。种族差异在高血压所致的推测性肾硬化症和II型糖尿病所致的肾病中尤为显著,但在多囊肾病或I型糖尿病所致的ESRD中尚未得到证实。现有数据不足以支持仅血压控制较差是导致ESRD发病种族差异的观点。黑人种族(可能还有墨西哥或美洲原住民血统)可能是ESRD的一个特定风险因素,与高血压及其治疗无关。

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