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马来西亚早期关于头颈部定位器在最初28例颅内和颅外部位精确放射治疗中应用的经验。

Early Malaysian experience on the use of head and neck localizers in the precision radiotherapy of intra and extra cranial sites for first 28 cases.

作者信息

Zamzuri I, Idris N R Nik, Mar W, Abdullah J M, Zakaria A, Biswal B M

机构信息

Department of Radiotherapy & Oncology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

出版信息

Med J Malaysia. 2006 Dec;61(5):621-5.

Abstract

Precision Radiotherapy at high doses require a fixed, referable target point. The frame system fulfills the required criteria by making the target point relocatable and fixed within a stereotactic space. Since December 2001, we have treated 28 central and peripheral nervous system lesions using either radiosurgery as a single high dose fraction or fractionated 3-dimensional conformal radiotherapy using a lower dose and a multi-leaf collimator. Various pathological lesions either benign or malignant were treated. Eighty six percent of our treated lesions showed growth restraint, preventing them from causing new symptoms with a median follow-up duration of 20.5 months. However, the true benefit from this technique would require a long-term follow-up to document the progress.

摘要

高剂量精确放疗需要一个固定的、可参照的靶点。框架系统通过使靶点在立体定向空间内可重新定位并固定,满足了所需标准。自2001年12月以来,我们使用单次高剂量分割的放射外科或使用较低剂量和多叶准直器的三维适形分割放疗,治疗了28例中枢和周围神经系统病变。治疗了各种良性或恶性的病理病变。我们治疗的病变中有86%显示出生长抑制,在中位随访期20.5个月内未出现新症状。然而,这项技术的真正益处需要长期随访来记录进展情况。

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