Migliano E, Monarca C, Mariani L, Tedesco M, Bucher S
Department of Plastic Surgery, IRCCS San Gallicano Institute IFO, Rome, Italy.
Eur J Gynaecol Oncol. 2007;28(3):229-32.
The case of a 54-year-old woman who developed vulvar melanoma arising from a melanocytic lesion, extending from the clitoris to the left labium minor, without clinical involvement of the groin node station bilaterally is presented. The patient first underwent an incisional diagnostic biopsy that revealed a melanoma 4 mm in thickness; subsequently preoperative lymphoscintigraphy with 99m Tc Nanocoll was executed. Surgery consisted of a radio-controlled lymphadenectomy and radical vulvectomy. Two bilateral subgluteus soft-tissue flaps were made to reconstruct the surgical defect, anastomosing the urethral and vaginal stump. At 36 months follow-up the patient was negative for neoplastic recurrence.
本文介绍了一名54岁女性的病例，该患者因黑素细胞病变发展为外阴黑色素瘤，病变从阴蒂延伸至左小阴唇，双侧腹股沟淋巴结未出现临床受累情况。患者首先接受了切开诊断性活检，结果显示为厚度4毫米的黑色素瘤；随后进行了99m锝纳米胶体术前淋巴闪烁显像。手术包括放射性控制的淋巴结清扫术和根治性外阴切除术。制作了两个双侧臀下软组织皮瓣来修复手术缺损，并吻合尿道和阴道残端。在36个月的随访中，患者肿瘤复发呈阴性。
