Huo Jun-Sheng, Yang Xiao-Guang, Piao Jian-Hua, Gao Jun-Quan, Miao Hong, Yu Bo, Lu Cheng-Qian, Chen Jun-Shi
Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Biomed Environ Sci. 2007 Apr;20(2):126-30.
NaFeEDTA was considered as a promising iron fortificant for controlling iron deficiency anemia. Soy sauce is a suitable food carrier for iron fortification and is a popular condiment in China. Iron absorption rates of NaFeEDTA and FeSO4 were observed and compared in adult female subjects.
The stable isotope tracer method was used in Chinese females consuming a typical Chinese diet. Ten healthy young Chinese women were selected as subjects in the 15-day study. A plant-based diet was used based on the dietary pattern of adult women in the 1992 National Nutrition Survey. Six milligram of 54Fe in 54FeSO4 soy sauce and 3 mg 58Fe in Na58FeEDTA soy sauce were given to the same subjects in two days. Food samples and fecal samples were collected and analyzed.
Iron absorption rates of NaFeEDTA and FeSO4 were 10.51% +/- 2.83 and 4.73% +/- 2.15 respectively. The 58Fe (NaFeEDTA) absorption was significantly higher than that of 54Fe (FeSO4) (P < 0.01). The iron absorption rate from NaFeEDTA was 1.2 times higher than that from FeSO4 in Chinese adult women consuming a typical Chinese diet.
The higher absorption rate of NaFeEDTA suggested that NaFeEDTA would be a better iron fortificant used in soy sauce for the controlling of iron deficiency anemia in China.
乙二胺四乙酸铁钠(NaFeEDTA)被认为是一种有前景的用于控制缺铁性贫血的铁强化剂。酱油是铁强化的合适食品载体,且在中国是一种受欢迎的调味品。观察并比较成年女性受试者中乙二胺四乙酸铁钠和硫酸亚铁的铁吸收率。
在中国女性食用典型中式饮食的情况下采用稳定同位素示踪法。在为期15天的研究中,选择10名健康的中国年轻女性作为受试者。根据1992年全国营养调查中成年女性的饮食模式采用以植物性食物为主的饮食。在两天内给同一受试者分别服用含6毫克54Fe的54FeSO4酱油和含3毫克58Fe的Na58FeEDTA酱油。收集并分析食物样本和粪便样本。
乙二胺四乙酸铁钠和硫酸亚铁的铁吸收率分别为10.51%±2.83和4.73%±2.15。58Fe(乙二胺四乙酸铁钠)的吸收率显著高于54Fe(硫酸亚铁)(P<0.01)。在食用典型中式饮食的中国成年女性中,乙二胺四乙酸铁钠的铁吸收率比硫酸亚铁高1.2倍。
乙二胺四乙酸铁钠较高的吸收率表明,乙二胺四乙酸铁钠将是一种用于酱油中更好的铁强化剂,可用于控制中国的缺铁性贫血。