青少年痤疮的管理

[Management of acne in adolescents].

作者信息

Faure M

机构信息

Service de dermatologie, hôpital Edouard-Herriot, pavillon R, 5, place d'Arsonval, 69437 Lyon cedex 03, France.

出版信息

Arch Pediatr. 2007 Sep;14(9):1152-6. doi: 10.1016/j.arcped.2007.05.011. Epub 2007 Jul 10.

DOI:10.1016/j.arcped.2007.05.011

PMID:17624743

Abstract

Acne is an androgen-dependant inflammatory folliculitis with non-inflammatory lesions (open and closed comedos) and inflammatory papules, pustules and sometimes nodules. Topical retinoïds, benzoyl peroxyde, antibiotics with anti-inflammatory properties, antiandrogens in female acne (antiandrogens and antiandrogenic oral contraceptives), and isotretinoin are the major drugs used in the management of the affection. Acne has to be treated according to the type of acne, severity, age and sex. Acne may also be the major sign of ovarian (PCOS) or adrenal hyperandrogenism in either female teenagers or both sexes, respectively.

摘要

痤疮是一种雄激素依赖性炎症性毛囊病，伴有非炎症性损害（开放性和闭合性粉刺）以及炎性丘疹、脓疱，有时还有结节。外用维甲酸、过氧化苯甲酰、具有抗炎特性的抗生素、女性痤疮中的抗雄激素药物（抗雄激素药物和抗雄激素口服避孕药）以及异维甲酸是治疗该病的主要药物。痤疮必须根据痤疮类型、严重程度、年龄和性别进行治疗。痤疮也可能分别是女性青少年或男女两性中卵巢（多囊卵巢综合征）或肾上腺雄激素过多症的主要体征。