Rodríguez Esequiel, Skarecky Douglas W, Ahlering Thomas E
Clinical Instructor & Robotics Fellow, Department of Urology, Universidad de California (Irvine), Orange, CA, USA.
Arch Esp Urol. 2007 May;60(4):421-9.
To review the current literature on oncologic outcomes following robot-assisted laparoscopic radical prostatectomy.
A systematic MEDLINE search was performed to retrieve articles relating to oncologic outcomes with robot-assisted laparoscopic prostatectomy. Two reviewers independently selected studies, assessed their methodological quality and extracted data.
Positive surgical margin rates in RALP are commensurate to contemporary open and standard laparoscopic series. Surgical experience and refinement of technique helped decrease positive margins. Long-term biochemical disease-free survival (PSA <0.1 ng/ml) following RALP is currently unknown, with only 2 series reporting data with > 12 month follow-up.
RALP is a safe and reproducible treatment modality for organ-confined prostate cancer and provides excellent short-term oncological control. Larger studies with long-term oncologic follow-up are needed to establish the efficacy compared to more traditional surgical approaches.
回顾当前关于机器人辅助腹腔镜根治性前列腺切除术后肿瘤学结局的文献。
进行系统的医学文献数据库（MEDLINE）检索，以获取与机器人辅助腹腔镜前列腺切除术肿瘤学结局相关的文章。两名评审员独立选择研究、评估其方法学质量并提取数据。
机器人辅助腹腔镜前列腺切除术（RALP）的手术切缘阳性率与当代开放性手术及标准腹腔镜手术系列相当。手术经验和技术改进有助于降低切缘阳性率。目前尚不清楚RALP术后长期无生化复发生存（前列腺特异性抗原[PSA]<0.1 ng/ml）情况，仅有2个系列报道了随访时间超过12个月的数据。
RALP是局限性前列腺癌的一种安全且可重复的治疗方式，能提供良好的短期肿瘤学控制。与更传统的手术方法相比，需要开展更大规模的长期肿瘤学随访研究来确定其疗效。
