Kaga A, Isono M, Mori T, Kusakabe T, Okada H, Hori S
Department of Neurosurgery, Medical College of Oita, Japan.
No Shinkei Geka. 1991 Nov;19(11):1079-83.
A first case of cavernous angioma of falx cerebri is reported. A 62-year-old woman who had a history of intermittent headache and dizziness was admitted to our hospital. On admission she had no neurological deficit, but CT scan showed a slightly high density tumor located beneath the falx cerebri. This was markedly and homogeneously enhanced by contrast medium. MRI showed a tumor with low intensity in T1-weighted image and high intensity speckled with low intensity in T2-weighted image. Angiogram revealed a faint tumor-stain fed by the bilateral pericallosal arteries at middle arterial to late venous phases. With the tumor attached to the lower edge, the falx was totally removed through a left front-parietal craniotomy. Histologically the tumor was diagnosed as cavernous angioma and thought to have originated from the dura mater of the falx. A search in the literature revealed that only 7 cases of extracerebral cavernous angiomas excluding ones in the middle cranial fossa have been previously reported. Five of them were located at the tentorium cerebelli and two at the convexity. The MRI finding such as speckled mixed intensity may reflect the vascular lumens or their thromboses in the tumor. Angiographic finding such as faint tumor stain at middle arterial to late venous phases due to slow blood flow in the tumor are thought to be specific to intracranial cavernous angiomas. These findings are of particular importance in differentiating cavernous angiomas from meningiomas.
本文报道了一例大脑镰海绵状血管瘤。一名62岁女性,有间歇性头痛和头晕病史,入住我院。入院时她没有神经功能缺损,但CT扫描显示大脑镰下方有一个略高密度的肿瘤。该肿瘤在注射造影剂后有明显且均匀的强化。MRI显示肿瘤在T1加权像上呈低信号,在T2加权像上呈高信号并伴有散在低信号。血管造影显示在动脉中期至静脉晚期,双侧胼周动脉为肿瘤提供淡染的肿瘤染色。由于肿瘤附着于大脑镰下缘,通过左额顶开颅术将大脑镰完全切除。组织学上,该肿瘤被诊断为海绵状血管瘤,推测起源于大脑镰的硬脑膜。文献检索发现,此前仅报道过7例颅外海绵状血管瘤(不包括中颅窝的病例)。其中5例位于小脑幕,2例位于脑凸面。肿瘤内散在混合信号强度等MRI表现可能反映肿瘤内的血管腔或血栓形成。肿瘤内血流缓慢导致动脉中期至静脉晚期出现淡染肿瘤染色等血管造影表现被认为是颅内海绵状血管瘤的特征性表现。这些表现对于鉴别海绵状血管瘤和脑膜瘤尤为重要。