Iourov Ivan Y, Liehr Thomas, Vorsanova Svetlana G, Yurov Yuri B
National Research Center of Mental Health, RAMS, Moscow, Russia.
Biomol Eng. 2007 Oct;24(4):415-7. doi: 10.1016/j.bioeng.2007.05.003. Epub 2007 May 31.
Biomedical research of interphase chromosomes in their integrity is hindered by technical limitations. We introduce a technology using microdissection-based engineering of DNA probes and fluorescence multicolor chromosome banding that allows studying interphase chromosome organization, numbers and rearrangements in somatic cells.
对完整的间期染色体进行生物医学研究受到技术限制的阻碍。我们引入了一种技术,该技术利用基于显微切割的DNA探针工程和荧光多色染色体显带技术,能够研究体细胞中间期染色体的组织、数量和重排。