Jonveaux P
Laboratoire Central d'Hématologie, Hôpital Saint-Louis, Paris, France.
Ann Genet. 1995;38(1):5-12.
A new microdissection and microcloning procedure of human banded chromosomes has been described. These micro-techniques allow the construction of band-specific DNA libraries, providing a large number of DNA probes for the identification of gene sequences. These technologies associated with fluorescence in situ hybridization studies are particularly efficient to analyse chromosomal regions involved in human genetic diseases including cancer.
已描述了一种新的人类带型染色体显微切割和微克隆程序。这些微技术可构建带特异性DNA文库，为基因序列的鉴定提供大量DNA探针。这些与荧光原位杂交研究相关的技术对于分析包括癌症在内的人类遗传疾病所涉及的染色体区域特别有效。
