Freedman J, Chamnongvongse P
Department of Ophthalmology, SUNY Health Science Center at Downstate, 161 Atlantic Avenue, Brooklyn, NY 11201, USA.
Br J Ophthalmol. 2008 May;92(5):669-72. doi: 10.1136/bjo.2007.115121. Epub 2007 Jul 12.
To describe clinical results of a new technique for inserting Molteno implants in a supra-Tenon's capsule location.
Prospective interventional case study.
19 patients, 18 of whom had suffered previous filter or glaucoma implant failure. Seventeen had open-angle glaucoma, and two had neovascular glaucoma. Seventeen patients were black and two were Asian.
All patients underwent supra-Tenon's capsule placement of a single-plate Molteno implant. Goldmann applanation tensions and Snellen visual acuities were determined before the operation and at the last follow-up visit. The numbers of preoperative and postoperative adjunctive drugs were compared before and after surgery.
Success was defined as intraocular pressure < or = 18 mm Hg with or without anti-glaucoma drugs.
Mean age was 62 years. Mean pressure before and after surgery was 31 and 16 mm Hg, respectively. Mean follow-up was 22 months (range 12-48). Vision returned to within 2 lines of preoperative vision, except in one patient who lost light perception. Surgery was regarded as a failure in four patients, including both patients with neovascular glaucoma. The difference between the median number of drugs used before (three) and after (one) the operation was significant (p<0.001). Complications were minimal, characterised by small choroidal effusions in three patients; all resolved spontaneously.
Supra-Tenon's capsule placement of Molteno implants in eyes with previously failed glaucoma surgery is an effective method for controlling intraocular pressure.
描述一种在眼球筋膜囊上方植入莫尔顿植入物的新技术的临床效果。
前瞻性干预性病例研究。
19例患者,其中18例曾有过滤过器或青光眼植入物失败史。17例为开角型青光眼,2例为新生血管性青光眼。17例患者为黑人,2例为亚洲人。
所有患者均在眼球筋膜囊上方植入单盘莫尔顿植入物。术前及最后一次随访时测定Goldmann压平眼压和Snellen视力。比较手术前后辅助用药的数量。
成功定义为使用或不使用抗青光眼药物时眼压≤18 mmHg。
平均年龄62岁。手术前后平均眼压分别为31 mmHg和16 mmHg。平均随访22个月(范围12 - 48个月)。除1例患者失去光感外,视力恢复至术前视力的2行以内。4例患者手术失败,包括2例新生血管性青光眼患者。手术前后使用药物中位数(术前3种,术后1种)差异有统计学意义(p<0.001)。并发症极少,3例患者出现少量脉络膜积液;均自行消退。
在既往青光眼手术失败的眼中,在眼球筋膜囊上方植入莫尔顿植入物是控制眼压的有效方法。