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[A pharmacokinetic basis for schedules for administering amikacin to newborn infants].

作者信息

Firsov A A, Sudilovskaia N N, Strachunskiĭ L S

出版信息

Pediatriia. 1991(8):33-8.

PMID:1762854
Abstract

The use of correlations between the pharmacokinetic parameters and the patient's factors is one of the most promising trends in the elaboration of the efficient regimens of dosage. To establish the analogous correlations in terms of specifying the causes of the widely known individual variability of serum aminoglycoside concentrations in 139 neonates given amikacin for suggested or documented infections, a study was made of the drug pharmacokinetics.

摘要

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