Chen Lei, Wang Gang, Wang Rong-Guang
Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Chinese People's Liberation Army, Beijing 100853, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007 May;42(5):341-4.
To explore the application of endoscopic endonasal approach in surgery for occupation lesions of the skull base.
Forty-two cases of skull base lesions treated by endoscopic endonasal surgery were analyzed retrospectively. There were 13 malignant tumors in anterior or middle cranial fossa, 8 chordoma, 5 invasive pituitary adenoma, 4 fibrous dysplasia of the sphenoid bone, 3 neurofibroma, 3 fibroangioma, 3 ossifying fibroma and 3 other lesions.
Lesions were removed completely in 36 patients, 2 of them were performed in two stages because of sever bleeding, and subtotally in 6 patients. The complications included 1 acroisa of right eye and 1 cerebrospinal fluid otorrhea. Follow-up ranged 6 to 81 months after the surgery. Five patents were lost of follow-up. Eight patients recurred and 6 patients died.
The endoscopic transnasal surgery is a safe, effective and minimally invasive approach to resect skull base lesions in condition of indications, surgeon's experience and the facilities.
探讨鼻内镜经鼻入路在颅底占位性病变手术中的应用。
回顾性分析42例经鼻内镜手术治疗的颅底病变患者。其中前颅窝或中颅窝恶性肿瘤13例，脊索瘤8例，侵袭性垂体腺瘤5例，蝶骨纤维发育不良4例，神经纤维瘤3例，纤维血管瘤3例，骨化性纤维瘤3例，其他病变3例。
36例患者病变完全切除，其中2例因出血严重分两期手术，6例次全切除。并发症包括右眼失明1例和脑脊液耳漏1例。术后随访6至81个月。5例失访。8例复发，6例死亡。
在有适应证、术者经验及设备条件下，鼻内镜经鼻手术是切除颅底病变安全、有效且微创的方法。
