Jacob Carlos Eduardo, Gama-Rodrigues Joaquim, Bresciani Claudio José Caldas, Zilberstein Bruno, Proscurshim Igor, Iriya Kiyoshi, Alves Venâncio Avancini Ferreira, Cecconello Ivan
Department of Gastroenterology, University of São Paulo, School of Medicine, Brazil.
Hepatogastroenterology. 2007 Jun;54(76):1297-301.
BACKGROUND/AIMS: Gastric cancer is still a leading cause of cancer death in the world and in Brazil. Historically a majority of gastric tumors were located in the distal third of the stomach. However, several studies have shown a shift in tumor location towards the proximal third.
Japanese rules for gastric cancer treatment were followed. All patients that were submitted to surgical resection for gastric cancer between 1971 and 1998 were included. These patients were divided into 3 time periods and classifled according to tumor location.
1021 patients underwent gastric resection for adenocarcinoma. The distal third of the stomach (53.7%) was the most common site. The proportion of tumors located in the proximal and middle thirds of the stomach increased significantly from 8.1% to 15% and 16.2 to 29.8% respectively at the last decade.
The findings of this study suggest an increase in the incidence of tumors to the proximal third of the stomach. However the high incidence of these tumors reported in literature is not confirmed.
背景/目的：在全球以及巴西，胃癌仍是导致癌症死亡的主要原因。从历史上看，大多数胃肿瘤位于胃的远端三分之一处。然而，多项研究表明肿瘤位置已向近端三分之一转移。
遵循日本胃癌治疗规则。纳入所有在1971年至1998年间接受胃癌手术切除的患者。这些患者被分为3个时间段，并根据肿瘤位置进行分类。
1021例患者接受了腺癌胃切除术。胃的远端三分之一（53.7%）是最常见的部位。在过去十年中，位于胃近端和中间三分之一的肿瘤比例分别从8.1%显著增加到15%，从16.2%增加到29.8%。
本研究结果表明胃近端三分之一处肿瘤的发病率有所增加。然而，文献中报道的这些肿瘤的高发病率并未得到证实。
