富尼耶坏疽及其在三级护理医院的治疗

Fournier's gangrene and its management at a tertiary care hospital.

作者信息

Fasih Qazi, Turi Mubasher H, Akram Mohammad

机构信息

Department of Urology and Transplantation, Jinnah Postgraduate Medical Centre, Karachi.

出版信息

J Pak Med Assoc. 2007 Jun;57(6):298-300.

PMID:17629231

Abstract

OBJECTIVE

To find the major causes of Fournier's gangrene and its management in a tertiary care hospital.

METHODS

A retrospective study was conducted at Department of Urology and Transplantation, JPMC, Karachi. Records of all patients with Fournier's Gangrene over 5 years' period i.e. from April 2001 till April 2006 were analysed.

RESULTS

The mean age was 48 years, all patients, presented with a delay of 2-16 days. Involvement was typical, with 70% extending to lower abdominal wall, and 10% to perianal region, while 37.5% were in septic shock. The cause of the gangrene was urological in 78.13%, followed by anorectal in 6.2% and idiopathic in 15.6%. Associated diseases were diabetes in 37.5%, uraemia in 12.5% and hepatic failure in 6.25%. Of all cases 12 died.

CONCLUSION

Aggressive surgical debridement with supportive measures is the main treatment. Twenty five percent patients died due to multiorgan failure in our study.

摘要

目的

探寻一家三级医疗机构中福尼尔坏疽的主要病因及其治疗方法。

方法

在卡拉奇真纳医学院泌尿外科与移植科开展了一项回顾性研究。分析了2001年4月至2006年4月这5年间所有福尼尔坏疽患者的病历。

结果

平均年龄为48岁，所有患者均延迟2至16天就诊。受累情况典型，70%扩展至下腹部壁，10%扩展至肛周区域，37.5%处于感染性休克状态。坏疽病因中78.13%为泌尿外科相关，其次6.2%为肛肠相关，15.6%为特发性。相关疾病包括37.5%的糖尿病、12.5%的尿毒症和6.25%的肝功能衰竭。所有病例中有12例死亡。