Al-Brahim Nabeel, Ceballos Kathy, Sur Monalisa, Daya Dean, Alowami Salem
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada L8N 3Z5.
Ann Diagn Pathol. 2007 Aug;11(4):282-4. doi: 10.1016/j.anndiagpath.2006.03.010.
Lipomembranous panniculitis is a peculiar type of fat necrosis and has been reported with several clinical conditions, commonly with peripheral vascular diseases. We are reporting a case of a 68-year-old woman with known liver cirrhosis and diabetes who presented with painful erythematous swelling of the right leg. Histological examination revealed microcystic changes within the subcutaneous fat. The microcysts were lined by acellular, eosinophilic membrane forming pseudopapillae and stained with periodic acid-Schiff stain. This histological feature is diagnostic of lipomembranous panniculitis. The pathologists should be aware of this entity because it aids the clinicians in investigating for associated clinical disorders.
脂膜性脂膜炎是一种特殊类型的脂肪坏死，已有报道与多种临床情况相关，常见于周围血管疾病。我们报告一例68岁已知肝硬化和糖尿病的女性患者，其出现右腿疼痛性红斑肿胀。组织学检查显示皮下脂肪内有微囊性改变。微囊肿内衬无细胞、嗜酸性膜，形成假乳头，并经高碘酸-希夫染色。这种组织学特征可诊断为脂膜性脂膜炎。病理学家应了解这一实体，因为它有助于临床医生调查相关的临床疾病。
