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宫颈妊娠:早期诊断与治疗的重要性

Cervical pregnancy: the importance of early diagnosis and treatment.

作者信息

Vela Gerardo, Tulandi Togas

机构信息

Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada.

出版信息

J Minim Invasive Gynecol. 2007 Jul-Aug;14(4):481-4. doi: 10.1016/j.jmig.2006.11.012.

Abstract

STUDY OBJECTIVE

To report the evolution and outcome of 12 cases of cervical pregnancy.

DESIGN

Retrospective study (Canadian Task Force classification II-3).

SETTING

University teaching hospitals.

PATIENTS

Twelve women with cervical pregnancy.

INTERVENTIONS

Methotrexate, uterine artery embolization, curettage, ligation of the descending branch of uterine vessels, or hysterectomy.

MEASUREMENTS AND MAIN RESULTS

The main outcome measure was success of conservative management. From January 1985 through December 2005, we encountered 12 cases of cervical pregnancy. The final diagnosis was established by ultrasound, operative findings, and histopathology. We obtained information from the medical records of the patients regarding when and how the diagnosis was made, the characteristics of the pregnancy, and treatment modalities. The prevalence of cervical pregnancy was 1:10,000 deliveries. The patients' history revealed previous curettage in 6 (50%) and cesarean delivery in 2 others (16.7%). Four patients (33.3%) initially not diagnosed to have cervical pregnancy required a hysterectomy. Initial diagnosis of cervical pregnancy was correct in 5 patients. They were treated with methotrexate, uterine artery embolization, curettage, or ligation of the descending branch of uterine vessels. None of these patients required blood transfusion or hysterectomy.

CONCLUSION

The success of conservative treatment for cervical pregnancy depends on the diagnostic accuracy of the initial ultrasound. Correct diagnosis would reduce the chance of hysterectomy or blood transfusion.

摘要

研究目的

报告12例宫颈妊娠的演变过程及结局。

设计

回顾性研究(加拿大工作组分类II - 3)。

地点

大学教学医院。

患者

12例宫颈妊娠女性。

干预措施

甲氨蝶呤、子宫动脉栓塞、刮宫术、子宫血管下行支结扎或子宫切除术。

测量指标及主要结果

主要结局指标为保守治疗的成功与否。1985年1月至2005年12月,我们共遇到12例宫颈妊娠。最终诊断通过超声、手术所见及组织病理学确定。我们从患者病历中获取了关于诊断时间及方式、妊娠特征和治疗方式的信息。宫颈妊娠的发生率为1:10,000分娩。患者病史显示,6例(50%)既往有刮宫史,另外2例(16.7%)有剖宫产史。4例最初未诊断为宫颈妊娠的患者需要行子宫切除术。5例患者宫颈妊娠的初始诊断正确。他们接受了甲氨蝶呤、子宫动脉栓塞、刮宫术或子宫血管下行支结扎治疗。这些患者均无需输血或子宫切除术。

结论

宫颈妊娠保守治疗的成功取决于初始超声诊断的准确性。正确诊断可减少子宫切除或输血的几率。

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