Horwath-Winter Jutta, Thaci Arsim, Gruber Anna, Boldin Ingrid
Department of Ophthalmology, Medical University of Graz, Graz, Austria.
Am J Ophthalmol. 2007 Sep;144(3):441-444. doi: 10.1016/j.ajo.2007.05.019. Epub 2007 Jul 12.
To evaluate long-term retention rates and complications of silicone punctal plugs among dry eye patients.
Prospective, observational cohort study.
Ninety-five silicone punctal plugs (FCI plugs; FCI Ophthalmics, Issy-les-Moulineaux Cedex, France) were placed in 93 eyes of 47 dry eye patients. Within the observation period of up to eight years, this survey included recording of the retention rate, spontaneous loss, removal, canalicular permeability after loss or removal, as well as other complications such as infection, intrusion, and granuloma.
The retention rate of the plugs was 84.2% after three months, 69.5% after one year, and 55.8% after a median of two years (range, 17 to 93 months). No infection was observed, but granulomatous formation occurred in three eyes (one with extrusion, two with intrusion). Three plugs had to be removed for local discomfort or epiphora, and one piece of a broken plug intruded. Canalicular stenosis after spontaneous loss occurred in 14.3% after three months, in 26.9% after one year, and in 34.2% after a median of two years.
The retention rate after a median of two years of FCI punctal plugs was satisfactory with few complications. The major observation concerned canalicular stenosis after spontaneous loss.
评估干眼症患者中硅胶泪点塞的长期留存率及并发症。
前瞻性观察队列研究。
将95个硅胶泪点塞（FCI塞；FCI眼科公司，法国伊西莱穆利诺 Cedex）植入47例干眼症患者的93只眼中。在长达8年的观察期内，本调查记录了留存率、自然脱落、取出情况，脱落或取出后的泪小管通透性，以及感染、侵入和肉芽肿等其他并发症。
3个月后塞子的留存率为84.2%，1年后为69.5%，中位2年（范围17至93个月）后为55.8%。未观察到感染，但3只眼中出现肉芽肿形成（1只伴有挤出，2只伴有侵入）。3个塞子因局部不适或溢泪而不得不取出，1个破碎塞子的碎片发生侵入。3个月后自然脱落导致泪小管狭窄的发生率为14.3%，1年后为26.9%，中位2年后为34.2%。
FCI泪点塞中位2年后的留存率令人满意，并发症较少。主要观察到的情况是自然脱落导致泪小管狭窄。
