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[特发性炎性肌病。31例患者分析]

[Idiopathic inflammatory myopathy. Analysis of 31 patients].

作者信息

Selva A, Cuenca R, San José A, Navarro C, Ordi J, Bosch J A, Alijotas J, Vilardell M

机构信息

Servicio de Medicina Interna, Hospital General Vall D'Hebron, Barcelona.

出版信息

Rev Clin Esp. 1991 Oct;189(6):260-3.

PMID:1763209
Abstract

A series of 31 patients suffering idiopathic inflammatory myopathy (IIM); we describe the extramuscular manifestations, specially pulmonary, the association to neoplasia, the histopathological characteristics, and their response to treatment. Fourty three percent of IIM patients presented a pulmonary involvement, 9% presented an associated neoplasia. The histopathological study allowed us to clearly differentiate dermatomyositis and polymyositis within IIM. 65% of patients initially responded to glucocorticoids and the most usefull therapeutic alternatives were azatioprine and cyclosporin-A.

摘要

一系列31例特发性炎性肌病(IIM)患者;我们描述了其肌肉外表现,特别是肺部表现、与肿瘤的关联、组织病理学特征及其对治疗的反应。43%的IIM患者出现肺部受累,9%出现相关肿瘤。组织病理学研究使我们能够在IIM中清楚地区分皮肌炎和多发性肌炎。65%的患者最初对糖皮质激素有反应,最有效的治疗替代药物是硫唑嘌呤和环孢素A。

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