Tayyab Neil A, Samartzis Dino, Altiok Haluk, Shuff Charles E, Lubicky John P, Herman Jean, Khanna Nitin
Girard Orthopaedic Surgeons, La Jolla, CA, USA.
Spine (Phila Pa 1976). 2007 Jul 15;32(16):E451-9. doi: 10.1097/BRS.0b013e3180ca7d2d.
A prospective, radiographic cohort study.
This study assessed the radiographic reliability and diagnostic value of the vertebral wedge ratio (WR) to the more segmental Cobb angle (CA) regarding sagittal spine deformities.
The use of the CA has been used to assist in the radiographic diagnosis of various sagittal spine deformities. However, the reliability and diagnostic aptitude of the CA remains speculative and may not be as receptive to individual variations of vertebral integrity in sagittal spine deformities.
Sixty patients (age range, 8-21 years) who were diagnosed with Scheuermann's kyphosis (Group 1; n = 16), with postural roundback (Group 2; n = 23), or who were regarded normal (Group 3; n = 21) were radiographically evaluated to assess the reliability and diagnostic potential of the vertebral WR (apex of the curve and 2 adjacent vertebrae) and segmental CA. Radiographic assessment was conducted by 3 independent blinded observers on 3 separate occasions.
Very strong intraobserver (WR a = 0.85-0.99; CA a = 0.97-0.99) and interobserver (WR a = 0.79-0.89; CA a = 0.95) reliabilities were noted. A greater degree of WR reliability was noted in Group 1, whereas CA reliability remained consistent in all Groups. A statistically significant difference was found between all Groups in relation to vertebral WR and segmental CA (P < 0.05). Based on relative risk ratio analyses, an apex wedge ratio of < or = 0.80 and/or a segmental Cobb angle of > or = 20 degrees is highly and significantly associated with Scheuermann's kyphosis.
The segmental CA exhibited a higher degree of reliability than the vertebral WR. The apex vertebral WR exhibited the greatest amount of wedging in the Scheuermann's patients; whereas in the other groups it remained largely consistent with the adjacent vertebral WRs. An apex vertebral WR < or = 0.80 and/or a segmental CA of > or = 20 degrees are highly associated with the clinical diagnosis of Scheuermann's kyphosis. If the segmental CA cannot be ascertained, the apex vertebral WR is a relatively strong reliable alternative, primarily with regards to Scheuermann's kyphosis. In addition, the type of deformity may potentially dictate the ideal measuring method.
一项前瞻性影像学队列研究。
本研究评估了椎体楔变率(WR)相对于节段性Cobb角(CA)在矢状位脊柱畸形方面的影像学可靠性及诊断价值。
CA已被用于辅助各种矢状位脊柱畸形的影像学诊断。然而,CA的可靠性和诊断能力仍存在推测性,在矢状位脊柱畸形中可能对椎体完整性的个体差异不太敏感。
对60例患者(年龄范围8 - 21岁)进行影像学评估,这些患者被诊断为休门氏后凸畸形(第1组;n = 16)、姿势性圆背(第2组;n = 23)或被认为正常(第3组;n = 21),以评估椎体WR(曲线顶点及相邻两个椎体)和节段性CA的可靠性及诊断潜力。影像学评估由3名独立的不知情观察者在3个不同时间进行。
观察者内可靠性非常高(WR α = 0.85 - 0.99;CA α = 0.97 - 0.99),观察者间可靠性也很高(WR α = 0.79 - 0.89;CA α = 0.95)。第1组中WR的可靠性程度更高,而CA的可靠性在所有组中保持一致。所有组在椎体WR和节段性CA方面存在统计学显著差异(P < 0.05)。基于相对风险比分析,顶点楔变率≤0.80和/或节段性Cobb角≥20度与休门氏后凸畸形高度且显著相关。
节段性CA比椎体WR表现出更高的可靠性。在休门氏病患者中,顶点椎体WR的楔变程度最大;而在其他组中,它与相邻椎体WR基本一致。顶点椎体WR≤0.80和/或节段性CA≥20度与休门氏后凸畸形的临床诊断高度相关。如果无法确定节段性CA,顶点椎体WR是一个相对可靠的替代指标,主要针对休门氏后凸畸形。此外,畸形类型可能决定理想的测量方法。