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用于人眼视网膜超高速光学相干断层扫描的1050纳米傅里叶域锁模,每秒236,000次轴向扫描。

Fourier domain mode locking at 1050 nm for ultra-high-speed optical coherence tomography of the human retina at 236,000 axial scans per second.

作者信息

Huber R, Adler D C, Srinivasan V J, Fujimoto J G

机构信息

Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

出版信息

Opt Lett. 2007 Jul 15;32(14):2049-51. doi: 10.1364/ol.32.002049.

Abstract

A Fourier domain mode-locked (FDML) laser at 1050 nm for ultra-high-speed optical coherence tomography (OCT) imaging of the human retina is demonstrated. Achievable performance, physical limitations, design rules, and scaling principles for FDML operation and component choice in this wavelength range are discussed. The fiber-based FDML laser operates at a sweep rate of 236 kHz over a 63 nm tuning range, with 7 mW average output power. Ultra-high-speed retinal imaging is demonstrated at 236,000 axial scans per second. This represents a speed improvement of approximately10x over typical high-speed OCT systems, paving the way for densely sampled volumetric data sets and new imaging protocols.

摘要

展示了一种用于人类视网膜超高速光学相干断层扫描(OCT)成像的1050 nm傅里叶域锁模(FDML)激光器。讨论了该波长范围内FDML操作和组件选择的可实现性能、物理限制、设计规则和缩放原理。基于光纤的FDML激光器在63 nm调谐范围内以236 kHz的扫描速率运行,平均输出功率为7 mW。每秒236,000次轴向扫描的超高速视网膜成像得到了展示。这比典型的高速OCT系统速度提高了约10倍,为密集采样的体积数据集和新的成像协议铺平了道路。

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