Tomita Hideshi, Hatakeyama Kinya, Soda Wataru, Kobayashi Toshiki
Department of Cardiology, Hokkaido Children's Hospital and Medical Center, Zenibako 1-10-1, Otaru, Hokkaido 047-0261.
J Cardiol. 2007 Jun;49(6):357-60.
Transcatheter closure of an atrial septal defect using the Amplatzer septal occluder is a current treatment option in Japan, but is occasionally associated with transient exacerbation or new onset migraine. Clopidogrel is effective in such a situation, but the efficacy of ticlopidine, an analog of clopidogrel, on migraine remains unclear. A 15-year-old girl presented with typical migraine attacks with aura 11 days after transcatheter closure of an atrial septal defect with an Amplatzer septal occluder. All examinations excluded thromboembolic origin of the migrain. Her symptoms disappeared completely after medication with ticlopidine.
在日本，使用Amplatzer房间隔封堵器经导管闭合房间隔缺损是一种当前的治疗选择，但偶尔会伴有短暂性病情加重或新发偏头痛。氯吡格雷在这种情况下有效，但氯吡格雷的类似物噻氯匹定对偏头痛的疗效仍不清楚。一名15岁女孩在使用Amplatzer房间隔封堵器经导管闭合房间隔缺损11天后出现伴有先兆的典型偏头痛发作。所有检查均排除了偏头痛的血栓栓塞性病因。她在服用噻氯匹定后症状完全消失。
