Stojakov D, Velicković D, Sabljak P, Bjelović M, Ebrahimi K, Spica B, Sljukić V, Pesko P
Centar za hirurgiju jednjaka, I Hirurska klinika, Institut za bolesti digestivnog sistema, KCS, Beograd.
Acta Chir Iugosl. 2007;54(1):125-9. doi: 10.2298/aci0701125s.
Dieulafoy's lesion is an unusual and potentially life-threatening cause of massive, recurrent gastrointestinal bleeding. Its reported incidence as a source of upper gastrointestinal bleeding ranges from 0.3-6.7%. Dieulafoy's lesion is most commonly located in the proximal stomach (75% of cases). Lesion typically occur within 6 to 10 cm of the esophagogastric junction, generally along the lesser curvature of the stomach. Similar lesions have been identified in the esophagus, duodenal bulb, jejunum, ileum, colorectum, anal canal, even in bronchus. Detection and identification of the Dieulafoy's lesion as the source of bleeding can often be difficult, especially because most present with massive bleeding. Because of intermittent nature of bleeding, initial endoscopy is diagnostic in 60% of the cases, so repeated endoscopies are often necessary. If the lesion can be endoscopically documented, attempts should be made to achieve hemostasis using one or a combination of several endoscopic modalities. Success has been reported with multipolar electrocoagulation, heater probe, noncontact laser photocoagulation, injection sclerotherapy, endoscopic hemoclipping and band ligation. Surgery is reserved for lesions that cannot be controlled by endoscopic techniques. When localized, a wide wedge resection of entire area traversed by the large submucosal artery is recomended because rebleeding has been described after simple coagulation and ligation.
迪厄拉富瓦病是导致大量反复胃肠道出血的一种罕见且可能危及生命的病因。据报道,其作为上消化道出血来源的发病率在0.3%至6.7%之间。迪厄拉富瓦病最常见于胃近端(75%的病例)。病变通常发生在食管胃交界处6至10厘米范围内,一般沿胃小弯处。在食管、十二指肠球部、空肠、回肠、结直肠、肛管甚至支气管中也发现过类似病变。将迪厄拉富瓦病确定为出血来源往往很困难,尤其是因为大多数患者表现为大量出血。由于出血具有间歇性,初次内镜检查在60%的病例中可明确诊断,因此常常需要反复进行内镜检查。如果病变能够通过内镜记录下来,应尝试使用一种或多种内镜方法进行止血。据报道,使用多极电凝、热探头、非接触激光光凝、注射硬化疗法、内镜下止血夹闭和套扎术已取得成功。手术适用于内镜技术无法控制的病变。当病变局限时,建议对大的黏膜下动脉穿过的整个区域进行广泛楔形切除,因为单纯凝固和结扎后曾有再出血的报道。