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[Dieulafoy病:大量上消化道出血的罕见病因]

[Dieulafoy's lesion: rare cause of massive upper gastrointestinal bleeding].

作者信息

Stojakov D, Velicković D, Sabljak P, Bjelović M, Ebrahimi K, Spica B, Sljukić V, Pesko P

机构信息

Centar za hirurgiju jednjaka, I Hirurska klinika, Institut za bolesti digestivnog sistema, KCS, Beograd.

出版信息

Acta Chir Iugosl. 2007;54(1):125-9. doi: 10.2298/aci0701125s.

DOI:10.2298/aci0701125s
PMID:17633872
Abstract

Dieulafoy's lesion is an unusual and potentially life-threatening cause of massive, recurrent gastrointestinal bleeding. Its reported incidence as a source of upper gastrointestinal bleeding ranges from 0.3-6.7%. Dieulafoy's lesion is most commonly located in the proximal stomach (75% of cases). Lesion typically occur within 6 to 10 cm of the esophagogastric junction, generally along the lesser curvature of the stomach. Similar lesions have been identified in the esophagus, duodenal bulb, jejunum, ileum, colorectum, anal canal, even in bronchus. Detection and identification of the Dieulafoy's lesion as the source of bleeding can often be difficult, especially because most present with massive bleeding. Because of intermittent nature of bleeding, initial endoscopy is diagnostic in 60% of the cases, so repeated endoscopies are often necessary. If the lesion can be endoscopically documented, attempts should be made to achieve hemostasis using one or a combination of several endoscopic modalities. Success has been reported with multipolar electrocoagulation, heater probe, noncontact laser photocoagulation, injection sclerotherapy, endoscopic hemoclipping and band ligation. Surgery is reserved for lesions that cannot be controlled by endoscopic techniques. When localized, a wide wedge resection of entire area traversed by the large submucosal artery is recomended because rebleeding has been described after simple coagulation and ligation.

摘要

迪厄拉富瓦病是导致大量反复胃肠道出血的一种罕见且可能危及生命的病因。据报道,其作为上消化道出血来源的发病率在0.3%至6.7%之间。迪厄拉富瓦病最常见于胃近端(75%的病例)。病变通常发生在食管胃交界处6至10厘米范围内,一般沿胃小弯处。在食管、十二指肠球部、空肠、回肠、结直肠、肛管甚至支气管中也发现过类似病变。将迪厄拉富瓦病确定为出血来源往往很困难,尤其是因为大多数患者表现为大量出血。由于出血具有间歇性,初次内镜检查在60%的病例中可明确诊断,因此常常需要反复进行内镜检查。如果病变能够通过内镜记录下来,应尝试使用一种或多种内镜方法进行止血。据报道,使用多极电凝、热探头、非接触激光光凝、注射硬化疗法、内镜下止血夹闭和套扎术已取得成功。手术适用于内镜技术无法控制的病变。当病变局限时,建议对大的黏膜下动脉穿过的整个区域进行广泛楔形切除,因为单纯凝固和结扎后曾有再出血的报道。

相似文献

1
[Dieulafoy's lesion: rare cause of massive upper gastrointestinal bleeding].[Dieulafoy病:大量上消化道出血的罕见病因]
Acta Chir Iugosl. 2007;54(1):125-9. doi: 10.2298/aci0701125s.
2
Outcomes of endoscopic treatment of gastroduodenal Dieulafoy's lesion with rubber band ligation and thermal/injection therapy.胃十二指肠Dieulafoy病损内镜下橡皮圈套扎术与热凝/注射治疗的疗效
J Clin Gastroenterol. 2003 Apr;36(4):310-4. doi: 10.1097/00004836-200304000-00006.
3
Clinical features and endoscopic management of Dieulafoy's disease.Dieulafoy病的临床特征及内镜治疗
Gastrointest Endosc. 1992 Sep-Oct;38(5):545-50. doi: 10.1016/s0016-5107(92)70513-6.
4
Gastric bleeding due to Dieulafoy's lesion, successfully treated by endoscopic hemoclipping.由Dieulafoy病变引起的胃出血,经内镜下止血夹成功治疗。
Rom J Gastroenterol. 2003 Jun;12(2):131-3.
5
Dieulafoy's lesion-like bleeding: an underrecognized cause of upper gastrointestinal hemorrhage in patients with advanced liver disease.Dieulafoy病样出血:晚期肝病患者上消化道出血的一个未被充分认识的原因。
Dig Dis Sci. 2007 Mar;52(3):722-6. doi: 10.1007/s10620-006-9468-7.
6
A prospective, randomized trial of endoscopic band ligation versus endoscopic hemoclip placement for bleeding gastric Dieulafoy's lesions.一项关于内镜下套扎术与内镜下止血夹放置术治疗胃Dieulafoy病出血的前瞻性随机试验。
Endoscopy. 2004 Aug;36(8):677-81. doi: 10.1055/s-2004-825661.
7
Rectal bleeding from a mucous fistula secondary to a Dieulafoy's lesion.继发于杜氏病损的黏液瘘导致的直肠出血。
J Clin Gastroenterol. 1997 Jun;24(4):259-61. doi: 10.1097/00004836-199706000-00017.
8
Endoscopic treatment and follow-up of gastrointestinal Dieulafoy's lesions.胃肠道Dieulafoy病损的内镜治疗及随访
World J Gastroenterol. 2005 Oct 14;11(38):6022-6. doi: 10.3748/wjg.v11.i38.6022.
9
[Dieulafoy's lesion as a cause of massive gastrointestinal hemorrhage].[Dieulafoy病作为大量胃肠道出血的病因]
G E N. 1990 Jan-Mar;44(1):59-62.
10
Gastric perforation after endoscopic treatment of a Dieulafoy's lesion.
Am J Gastroenterol. 1992 Feb;87(2):244-7.

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Use of Over-the-Scope Clip as First Choice to Treat Gastric Dieulafoy Lesions.将圈套器夹作为治疗胃Dieulafoy病变的首选方法。
Middle East J Dig Dis. 2021 Apr;13(2):163-165. doi: 10.34172/mejdd.2021.221. Epub 2021 May 29.