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[十二指肠溃疡出血的内镜止血]

[Endoscopic haemostasis of bleeding duodenal ulcer].

作者信息

Popović D, Stanković-Popović V, Jovanović I, Krstić M, Djuranović S, Mijalković N, Milosavljević T, Pavlović A, Culafić Dj, Sokić-Milutinović A, Milisić M

机构信息

Klinika za gastroenterologiju i hepatologiju, KCS.

出版信息

Acta Chir Iugosl. 2007;54(1):145-50. doi: 10.2298/aci0701145p.

Abstract

INTRODUCTION

Acute upper gastrointestinal bleeding is the commonest emergency managed by gastroenterologists. It manifests like: haematemesis, melaena or haemochezia. Diagnostic endoscopy accurately defining the cause of haemorrhage, while therapeutic endoscopy improves prognosis in patients who present with severe bleeding. Endoscopic therapies can be classified as those based on injection, application of heat, or mechanical clips.

PATIENTS AND METHODS

This investigation was conducted in Department of endoscopic haemostasis, Clinic for gastroenterology and hepatology, CCS, using retrospective analysis of patients with acute upper gastrointestinal bleeding during the last five years. The aim of this study was to establish the number of upper gastrointestinal bleeding in our hospital during the last five years, and distribution of income according to type, difficulty, cause factors and risk factors of gastrointestinal bleeding and method of haemostasis.

RESULTS

In Department of endoscopic haemostasis 3954 patients with upper gastrointestinal bleeding were endoscoped, and 33.4% of them had bleeding duodenal ulcer. Male patients were statistically significant more present than female patients in group with duodenal ulcer 71.8%: 28.2%). 79.7% patients with duodenal ulcer had only haematemesis, while 14.4% patients had haematemesis and melaena. 59.1% patients with bleeding duodenal ulcer consumed salicylates and/or non-steroidal anti-inflammatory drugs (NSAIDS) (statistical significant differences chi2 test; p = 0.007). Only endoscopic injection was used: in 36.8% of patients used injection of adrenaline solutions, while in 5.9% of patients used injection of adrenaline and absolute alcohol solutions.

CONCLUSION

Using of therapeutic endoscopy improves better prognosis in patients who present with severe acute upper gastrointestinal bleeding. Endoscopist's experience is an important independent prognostic factor for acute upper gastrointestinal bleeding.

摘要

引言

急性上消化道出血是胃肠病学家处理的最常见急症。其表现为:呕血、黑便或便血。诊断性内镜检查能准确确定出血原因,而治疗性内镜检查可改善严重出血患者的预后。内镜治疗可分为基于注射、热应用或机械夹子的治疗。

患者与方法

本研究在CCS胃肠病与肝病诊所的内镜止血科进行,采用回顾性分析过去五年中急性上消化道出血患者的情况。本研究的目的是确定我院过去五年中上消化道出血的病例数,以及根据胃肠道出血的类型、难度、病因因素和风险因素及止血方法的收入分布情况。

结果

在内镜止血科,对3954例上消化道出血患者进行了内镜检查,其中33.4%患有十二指肠溃疡出血。十二指肠溃疡组男性患者在统计学上显著多于女性患者(71.8%:28.2%)。79.7%的十二指肠溃疡患者仅有呕血,而14.4%的患者有呕血和黑便。59.1%的十二指肠溃疡出血患者使用了水杨酸盐和/或非甾体抗炎药(NSAIDS)(卡方检验有统计学显著差异;p = 0.007)。仅使用了内镜注射:36.8%的患者使用肾上腺素溶液注射,而5.9%的患者使用肾上腺素和无水乙醇溶液注射。

结论

对于严重急性上消化道出血患者,使用治疗性内镜检查可改善预后。内镜医师的经验是急性上消化道出血的一个重要独立预后因素。

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