Fabbri Gianna, Gorini Marco, Maggioni Aldo P, Oliva Fabrizio
Centro di Coordinamento Registro IN-CHF, Centro Studi ANMCO, Via La Marmora, 34 50121 Firenze.
G Ital Cardiol (Rome). 2007 Jun;8(6):353-8.
Heart failure remains a growing public health problem, hospitalizations represent the main cost component of heart failure care and the poor quality of life of patients is often worsened by frequent admissions. A multidisciplinary approach and specific disease management programs are a potentially useful instrument to reducing hospitalizations in heart failure patients. These concepts have recently been discussed in a consensus document by all the Scientific Societies involved in the care of heart failure patients. The effectiveness of intervention programs delivering continuity of care by a multidisciplinary team achieved a promising reduction in admissions, but the results of the studies have not been univocal for category of strategies and about the effect on survival. Telephone intervention significantly decreased heart failure admissions but not all-cause admissions and mortality. The multicenter randomized DIAL study, comparing a centralized telephone intervention program delivering continuity of care by a multidisciplinary team with usual care in patients with heart failure, confirms these findings. After a mean 16-month follow-up, there was a benefit mostly due to a significant reduction in admissions for heart failure, but mortality was similar in both groups. Data on 9000 patients from the IN-CHF registry show that hospitalizations are a serious problem in Italy: 44% of the patients had at least one hospitalization for heart failure in the year prior to the entry visit and this is the most powerful independent predictor of rehospitalization during the follow-up. Nearly a quarter of the population with follow-up data availability (92%) has been rehospitalized in the year after enrollment; patients in advanced functional class (32.1% hospitalization rate) and with ischemic etiology (25.0%) are more likely to be hospitalized than those in NYHA class I-II and without ischemic etiology. In a survey carried out recently in Italy, in 1152 patients admitted for decompensated heart failure, readmission rate was even higher: more than 40% of patients have been readmitted once in the 6 months after discharge and 7.2% had two or more admissions.
心力衰竭仍是一个日益严重的公共卫生问题,住院治疗是心力衰竭护理的主要成本组成部分,而频繁入院往往会使患者的生活质量恶化。多学科方法和特定疾病管理计划是减少心力衰竭患者住院次数的潜在有用手段。这些概念最近在一份由所有参与心力衰竭患者护理的科学学会共同撰写的共识文件中进行了讨论。由多学科团队提供持续护理的干预计划的有效性在减少入院次数方面取得了令人鼓舞的成果,但研究结果在策略类别以及对生存率的影响方面并不一致。电话干预显著降低了心力衰竭的入院次数,但并未降低全因入院次数和死亡率。多中心随机DIAL研究将由多学科团队提供持续护理的集中式电话干预计划与心力衰竭患者的常规护理进行了比较,证实了这些发现。经过平均16个月的随访,出现了益处,主要是由于心力衰竭入院次数显著减少,但两组的死亡率相似。来自IN-CHF注册研究的9000名患者的数据显示,住院治疗在意大利是一个严重问题:44%的患者在入组前一年至少因心力衰竭住院一次,这是随访期间再次住院的最有力独立预测因素。在有随访数据的近四分之一人口(92%)中,在入组后的一年里再次住院;功能分级较高(住院率32.1%)和患有缺血性病因(25.0%)的患者比纽约心脏协会I-II级且无缺血性病因的患者更易住院。在意大利最近进行的一项调查中,在1152名因失代偿性心力衰竭入院的患者中,再入院率甚至更高:超过40%的患者在出院后6个月内再次入院一次,7.2%的患者有两次或更多次入院。