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一项针对老年心力衰竭患者疾病管理项目的前瞻性对照研究的两年结果。

Two-year outcome of a prospective, controlled study of a disease management programme for elderly patients with heart failure.

作者信息

Del Sindaco Donatella, Pulignano Giovanni, Minardi Giovanni, Apostoli Antonella, Guerrieri Luca, Rotoloni Marina, Petri Gabriella, Fabrizi Lino, Caroselli Attilia, Venusti Rita, Chiantera Angelo, Giulivi Alessia, Giovannini Ezio, Leggio Francesco

机构信息

Division of Cardiology, Cardiogeriatric Department, INRCA Institute of Care and Research, Rome, Italy.

出版信息

J Cardiovasc Med (Hagerstown). 2007 May;8(5):324-9. doi: 10.2459/JCM.0b013e32801164cb.

Abstract

OBJECTIVE

Elderly heart failure patients are at high risk of events. Available studies and systematic reviews suggest that elderly patients benefit from disease management programmes (DMPs). However, important questions remain open, including the optimal follow-up intensity and duration and whether such interventions are cost-effective during long-term follow-up and in different healthcare systems. The aim of this study was to determine the long-term efficacy of a hybrid DMP in consecutive older outpatients.

METHODS

Intervention consisted in combined hospital-based (cardiologists and nurse-coordinators from two heart failure clinics) and home-based (patient's general practitioner visits) care. The components of the DMP were the following: discharge planning, education, therapy optimisation, improved communication, early attention to signs and symptoms. Intensive follow-up was based on scheduled hospital visits (starting within 14 days of discharge), nurse's phone call and home general practitioner visits.

RESULTS

A group of 173 patients aged > or =70 years (mean age 77 +/- 6 years, 48% women) was randomly assigned to DMP (n = 86) or usual care (n = 87). At 2-year follow-up, a 36% reduction in all-cause death and heart failure hospital admissions was observed in DMP vs. usual care. All-cause and heart failure admissions as well as the length of hospital stay were also reduced. DMP patients reported, compared to baseline, significant improvements in functional status, quality of life and beta-blocker prescription rate. The intervention was cost-effective with a mean saving of euro 982.04 per patient enrolled.

CONCLUSIONS

A hybrid DMP for elderly heart failure patients improves outcomes and is cost-effective over a long-term follow-up.

摘要

目的

老年心力衰竭患者发生不良事件的风险很高。现有研究和系统评价表明,老年患者可从疾病管理项目(DMPs)中获益。然而,一些重要问题仍未解决,包括最佳随访强度和持续时间,以及此类干预措施在长期随访中以及在不同医疗系统中是否具有成本效益。本研究的目的是确定一种混合DMP对连续性老年门诊患者的长期疗效。

方法

干预措施包括基于医院的(来自两家心力衰竭诊所的心脏病专家和护士协调员)和基于家庭的(患者的全科医生出诊)护理相结合。DMP的组成部分如下:出院计划、教育、治疗优化、改善沟通、早期关注体征和症状。强化随访基于定期的医院就诊(出院后14天内开始)、护士电话随访和家庭全科医生出诊。

结果

一组173名年龄≥70岁的患者(平均年龄77±6岁,48%为女性)被随机分配至DMP组(n = 86)或常规护理组(n = 87)。在2年随访时,与常规护理相比,DMP组全因死亡和心力衰竭住院率降低了36%。全因和心力衰竭住院次数以及住院时间也有所减少。与基线相比,DMP组患者在功能状态、生活质量和β受体阻滞剂处方率方面有显著改善。该干预措施具有成本效益,每名入组患者平均节省982.04欧元。

结论

针对老年心力衰竭患者的混合DMP可改善预后,且在长期随访中具有成本效益。

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