de Greeff S C, Sanders E A M, de Melker H E, van der Ende A, Vermeer P E, Schouls L M
Rijksinstituut voor Volksgezondheid en Milieu, Centrum voor Infectieziektebestrijding, Postbak 75, Postbus 1, 3720 BA Bilthoven.
Ned Tijdschr Geneeskd. 2007 Jun 30;151(26):1454-7.
Despite the availability of antibiotics and the care offered by intensive-care units, invasive pneumococcal disease still causes serious illness with high morbidity and mortality. Currently, two vaccines are available in the Netherlands that offer protection against invasive pneumococcal disease: a 7-valent conjugated vaccine and a 23-valent polysaccharide vaccine. Case reports and pharmaceutical use as registered by the Foundation for Pharmaceutical Statistics (SFK) show that general practitioners and pharmacists are not always aware of the appropriate use of both vaccines. For vaccination against pneumococci in children aged 0-5 years, general practitioners should prescribe only the conjugated vaccine. The non-conjugated polysaccharide vaccine is intended especially for the elderly and specific groups at risk. Pharmacists should verify that the pneumococcal vaccines they hand out on prescription are recommended for the age-group of the individuals to whom the vaccine will be administered.
尽管有抗生素可用，且重症监护病房也提供了相应护理，但侵袭性肺炎球菌疾病仍会引发严重疾病，发病率和死亡率都很高。目前，荷兰有两种疫苗可预防侵袭性肺炎球菌疾病：一种7价结合疫苗和一种23价多糖疫苗。病例报告以及药物统计基金会（SFK）登记的药品使用情况表明，全科医生和药剂师并非总能意识到这两种疫苗的正确使用方法。对于0至5岁儿童的肺炎球菌疫苗接种，全科医生应仅开具结合疫苗。非结合多糖疫苗专门针对老年人和特定风险群体。药剂师应核实他们根据处方发放的肺炎球菌疫苗是否是为将接种该疫苗的个人所在年龄组推荐使用的。
