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复方丹参滴丸治疗糖尿病视网膜病变的临床研究

[Clinical study of diabetic retinopathy treated by compound danshen dripping pills].

作者信息

Qi Chao-xiu, Tan Xu-hua, Li Qi-gen, Wang Xiao-li

机构信息

(Department of Ophthalmology, Affiliated Third Hospital, Sun Yat-sen University, Guangzhou 510630, China.

出版信息

Zhong Yao Cai. 2007 Mar;30(3):375-7.

PMID:17634050
Abstract

OBJECTIVE

To observe the therapeutic effect of compound danshen dripping pills in visual function recovery of diabetic retinopathy.

METHODS

42 patients(78 eyes) with diabetic retinopathy of I-III phase were divided into two groups in random. 43 eyes were treated with compound danshen dripping pills and the other 35 eyes with vitamin BI and Luding C for three months. The visual acuity, fundus, visual field, fundus fluorescein angiography and visual electro-physiology were observed.

RESULTS

The visual acuity in treated group were significantly improved after treatment and had significant difference with those in control group (P < 0.05). The number of micro-hemorrage, microaneurysm and the mean defect (MD) of visual field in treated group decreased obviously after treatment and had significant difference with that in control group (P < 0.05). The latent period of P100 wave and a, b wave in treated group were shorter than control group, and the wave amplitude were higher than that in control group.

CONCLUSION

The compound danshen dripping pills can improve the visual acuity, control the micro-hemorrage and microaneurysm of fundus and have the effect in visual function recovery of diabetic retinopathy.

摘要

目的

观察复方丹参滴丸对糖尿病视网膜病变视功能恢复的治疗效果。

方法

将42例(78只眼)Ⅰ - Ⅲ期糖尿病视网膜病变患者随机分为两组。43只眼采用复方丹参滴丸治疗,另35只眼采用维生素B1和芦丁C治疗,为期三个月。观察视力、眼底、视野、眼底荧光血管造影及视觉电生理情况。

结果

治疗组治疗后视力显著提高,与对照组相比有显著差异(P < 0.05)。治疗组治疗后眼底微出血、微动脉瘤数量及视野平均缺损(MD)明显减少,与对照组相比有显著差异(P < 0.05)。治疗组P100波、a波和b波的潜伏期短于对照组,波幅高于对照组。

结论

复方丹参滴丸可提高糖尿病视网膜病变患者的视力,控制眼底微出血和微动脉瘤,对视功能恢复有一定作用。

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