El-Sakka Ahmed I, Morsy Ayman M, Fagih Bassam I
Department of Urology, Suez Canal University, Ismailia, Egypt.
J Sex Med. 2007 Sep;4(5):1448-53. doi: 10.1111/j.1743-6109.2007.00550.x. Epub 2007 Jul 18.
Enhanced external counterpulsation (EECP) is a noninvasive outpatient treatment used for patients with intractable angina refractory to aggressive surgical and medical treatment. Recent results have demonstrated a positive impact of EECP on patients with ischemic heart disease (IHD)-associated erectile dysfunction (ED).
To assess the effect of IHD duration and number of EECP courses on efficacy and satisfaction rate of EECP on patients with IHD-associated ED.
We compared pre- and post-EECP responses to erectile function (EF) domain, Q3 and Q4 of the International Index of Erectile Function score in patients who received one or two courses of EECP and those who had <5- or >or=5-years duration of IHD.
As mentioned in part I a total of 44 male patients with intractable angina caused by coronary insufficiency were enrolled in this study. Treatment course of EECP consists of 35 1-hour sessions over 7 weeks. Another 35 1-hour sessions over another 7 weeks were offered to patients who received one course and required a second course because of no or minimal improvement from class IV to class III angina after the first course.
Patients who received only one course (N = 34) had significantly higher EF domain, Q3 and Q4, in pre- and post-EECP results than patients who received two courses (N = 10) after they completed the first course. Patients who had <5-years duration of IHD had significantly higher pre- and post EECP than patients who had >or=5 years regarding EF domain, Q3 and Q4. Considering the global efficacy question, overall satisfaction, and angina, there were significant improvements of post EECP in patients with <5 years than in patients with >or=5-years duration of IHD.
The efficacy and satisfaction rate of EECP in patients with IHD-associated ED were negatively influenced by longer duration of IHD and requirement of a second course of EECP.
增强型体外反搏（EECP）是一种非侵入性门诊治疗方法，用于那些对积极的手术和药物治疗无效的顽固性心绞痛患者。最近的研究结果表明，EECP对缺血性心脏病（IHD）相关的勃起功能障碍（ED）患者有积极影响。
评估IHD病程和EECP疗程数量对IHD相关ED患者EECP疗效和满意度的影响。
我们比较了接受一疗程或两疗程EECP的患者以及IHD病程<5年或≥5年的患者在EECP前后勃起功能（EF）领域、国际勃起功能指数评分的Q3和Q4的反应。
如第一部分所述，本研究共纳入44例因冠状动脉供血不足导致顽固性心绞痛的男性患者。EECP治疗疗程包括在7周内进行35次1小时的治疗。对于接受一疗程治疗且因第一疗程后心绞痛症状从IV级改善至III级不明显或无改善而需要第二疗程的患者，再给予另外7周的35次1小时治疗。
仅接受一疗程（N = 34）的患者在完成第一疗程后，EECP前后的EF领域、Q3和Q4显著高于接受两疗程（N = 10）的患者。IHD病程<5年的患者在EECP前后的EF领域、Q3和Q4显著高于病程≥5年的患者。考虑到总体疗效问题、总体满意度和心绞痛情况，IHD病程<5年的患者EECP后的改善情况显著优于病程≥5年的患者。
IHD相关ED患者EECP的疗效和满意度受到IHD病程延长和需要第二疗程EECP的负面影响。
