Bergmann T, Bölükbas S, Beqiri S, Trainer S, Schirren J
Klinik für Thoraxchirurgie, HSK, Dr-Horst-Schmidt-Kliniken, Wiesbaden.
Chirurg. 2007 Aug;78(8):687-97. doi: 10.1007/s00104-007-1379-4.
Solitary pulmonary nodules (SPN) are radiologically defined as intraparenchymal lung lesions not bigger then 3 cm. In general all pulmonary nodules should be considered malignant until proven otherwise. Primary peripheral lung cancer is the most common cause, at 40%. The probability that an SPN is malignant increases with patient age. Spiral chest CT is the ideal imaging to indicate the precise anatomical location and expose other pathological findings. Malignant SPN can also persist without change for over 2 years. Only complete histological examination can exclude malignance. Therefore every SPN should be resected in operable patients. The surgical risk of video-assisted pulmonary resection and diagnostic thoracotomy is low. For patients who are not operable, other diagnostic procedures such as transthoracic needle aspiration or positron emission tomography may be helpful.
孤立性肺结节(SPN)在影像学上被定义为实质内肺病变,直径不超过3厘米。一般来说,在未被证明为其他情况之前,所有肺结节都应被视为恶性。原发性周围型肺癌是最常见的病因,占40%。SPN为恶性的概率随患者年龄增加而升高。螺旋胸部CT是显示精确解剖位置并发现其他病理表现的理想影像学检查。恶性SPN也可能持续两年以上无变化。只有完整的组织学检查才能排除恶性。因此,对于可手术的患者,每个SPN都应进行切除。电视辅助肺切除和诊断性开胸手术的手术风险较低。对于不可手术的患者,其他诊断程序如经胸针吸活检或正电子发射断层扫描可能会有帮助。