Jasonni V M, Raffelli R, de March A, Frank G, Flamigni C
Department of Obstetrics and Gynecology, University of Bologna, Italy.
Acta Obstet Gynecol Scand. 1991;70(6):493-5. doi: 10.3109/00016349109007166.
Fifteen hyperprolactinemic and 7 puerperal women were treated with bromocriptine per vaginam (2.5-5 mg) because of absolute intolerance to the oral administration of this drug. In both groups the prolactinemia was normalized without the typical side effects of bromocriptine. Three patients reported vaginal burning, but only one discontinued the therapy because of the intensity of the symptom. This study suggests that vaginal bromocriptine should be considered as a useful alternative for the treatment of hyperprolactinemia.
15名高催乳素血症患者和7名产后妇女因对溴隐亭口服给药存在绝对不耐受，接受了经阴道给予溴隐亭（2.5 - 5毫克）的治疗。在两组中，催乳素血症均恢复正常，且未出现溴隐亭的典型副作用。3名患者报告有阴道烧灼感，但只有1名患者因症状严重而停止治疗。本研究表明，阴道用溴隐亭应被视为治疗高催乳素血症的一种有效替代方法。
