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[每周紫杉醇化疗成功治疗晚期胃癌病例]

[Case of advanced gastric cancer successfully treated with chemotherapy of weekly paclitaxel].

作者信息

Fujii Kyoko, Uno Hironori, Kayo Soichiro, Ueda Yoshio, Kawamura Chika, Mizuyama Yoko, Kaneda Koji, Nakagawa Hiroji, Arakawa Tetsuo

机构信息

Dept. of Gastroenterology, Ohno-Kinen Hospital.

出版信息

Gan To Kagaku Ryoho. 2007 Jul;34(7):1107-9.

PMID:17637550
Abstract

We report a case of gastric cancer with ascites treated with chemotherapy. The patient is a 67-year-old male. Combination chemotherapy of S-1 and CDDP was given as the first-line treatment. However, the symptoms did not improve with that regimen, so we decided to change the chemotherapy to paclitaxel as second-line treatment. After 4 cycles, CT scan revealed decreasing ascites and endoscopy a reduction of the primary tumor. The patient has maintained a condition of decreasing ascites with improvement of QOL for 8 months. This regimen is considered effective treatment for unresectable gastric cancer.

摘要

我们报告了一例接受化疗治疗的伴有腹水的胃癌病例。患者为一名67岁男性。一线治疗采用S-1与顺铂联合化疗。然而,该方案未能改善症状,因此我们决定将化疗改为紫杉醇作为二线治疗。4个周期后,CT扫描显示腹水减少,内镜检查显示原发肿瘤缩小。患者腹水减少且生活质量改善的状态已维持了8个月。该方案被认为是治疗不可切除胃癌的有效方法。

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