Lloyd A, Penson D, Dewilde S, Kleinman L
Center for Health Outcomes Research, United BioSource Corporation, 20 Bloomsbury Square, London, WC1A 2NS, UK.
Prostate Cancer Prostatic Dis. 2008;11(2):153-9. doi: 10.1038/sj.pcan.4500992. Epub 2007 Jul 17.
Treatment choices for metastatic prostate cancer are complex and can involve men balancing survival versus quality of life. The present study aims to elicit patient preferences with respect to the attributes of treatments for metastatic prostate cancer through a discrete choice experiment (DCE) questionnaire. Men with recently diagnosed localized prostate cancer were asked to envisage that they had metastatic disease when completing a survey. As expected, men with prostate cancer placed considerable importance on gains in survival; however, avoiding side effects of treatment was also clearly important. Survival gains should be considered alongside side effects when discussing treatment options in metastatic disease.
转移性前列腺癌的治疗选择很复杂,可能需要患者在生存和生活质量之间进行权衡。本研究旨在通过离散选择实验(DCE)问卷,了解患者对转移性前列腺癌治疗属性的偏好。要求近期诊断为局限性前列腺癌的男性在完成调查时设想自己患有转移性疾病。正如预期的那样,前列腺癌患者非常重视生存获益;然而,避免治疗副作用显然也很重要。在讨论转移性疾病的治疗方案时,应将生存获益与副作用一并考虑。