Derumeaux G, Lenormand C, Remadi F, Cribier A, Letac B
Service de cardiologie, hôpital Charles-Nicolle, Rouen.
Arch Mal Coeur Vaiss. 1991 Nov;84(11):1555-60.
The aim of this study was to evaluate the continuity equation in the quantification of mitral valve area in mitral stenosis, the area being considered as the product of the area of the left ventricular outflow tract multiplied by the ratio of the velocity time integrals of the aortic or pulmonary flow to that mitral flow. The continuity equation was compared to two other echocardiographic methods, planimetry and Hatle's method, and to the results obtained at catheterization using the Gorlin formula in a population of 44 patients with mitral stenosis. All were in sinus rhythm; twelve had Grade I mitral regurgitation and 9 patients had Grade I aortic regurgitation. Excellent correlation were observed between the values obtained by the continuity equation and planimetry (r = 0.91; SEE = 0.19 cm2; p less than 0.001) and Hatle's method (r = 0.87; SEE = 0.20 cm2, p less than 0.001). The correlation with the catheter values were also excellent (r = 0.83; SD = 0.22 cm2, p less than 0.001), better than those observed with Hatle's method (r = 0.73; SEE = 0.27 cm2, p less than 0.001) and very similar to those obtained with planimetry (r = 0.87; SEE = 0.23 cm2, p less than 0.001). The sensibility and specificity of the continuity equation for the diagnosis of severe mitral stenosis (surface less than 1.5 cm2) were 90% and 100% respectively, when those of Hatle's method were 88% and 91% respectively. The continuity equation in the evaluation of mitral valve area in mitral stenosis seems to be reliable and accurate compared with catheter data, and superior to Hatle's method.
本研究的目的是评估连续性方程在二尖瓣狭窄二尖瓣瓣口面积定量中的应用,该瓣口面积被视为左心室流出道面积乘以主动脉或肺血流与二尖瓣血流速度时间积分的比值。将连续性方程与其他两种超声心动图方法(平面测量法和哈特利法)以及在44例二尖瓣狭窄患者中使用戈林公式通过心导管检查获得的结果进行比较。所有患者均为窦性心律;12例有Ⅰ级二尖瓣反流,9例有Ⅰ级主动脉反流。连续性方程与平面测量法(r = 0.91;标准估计误差 = 0.19 cm²;p < 0.001)和哈特利法(r = 0.87;标准估计误差 = 0.20 cm²,p < 0.001)所得值之间观察到极好的相关性。与心导管检查值的相关性也很好(r = 0.83;标准差 = 0.22 cm²,p < 0.001),优于哈特利法(r = 0.73;标准估计误差 = 0.27 cm²,p < 0.001),且与平面测量法所得结果非常相似(r = 0.87;标准估计误差 = 0.23 cm²,p < 0.001)。连续性方程诊断重度二尖瓣狭窄(瓣口面积小于1.5 cm²)的敏感性和特异性分别为90%和100%,而哈特利法的敏感性和特异性分别为88%和91%。与心导管检查数据相比,连续性方程在评估二尖瓣狭窄二尖瓣瓣口面积方面似乎可靠且准确,并且优于哈特利法。