Terävä Anna-Niina, Gissler Mika, Hemminki Elina, Luoto Riitta
School of Public Health, University of Tampere, Medisiinarinkatu 3, 33520 Tampere, Finland.
Eur J Obstet Gynecol Reprod Biol. 2008 Jan;136(1):61-6. doi: 10.1016/j.ejogrb.2007.05.009. Epub 2007 Jul 20.
To examine changes in the use of infertility treatments by time, the causes of infertility, lifetime prevalence of subfertility, and the use of infertility treatments by socio-demographic factors.
Aggregate IVF statistics (1992-2004) and two nationally representative cross-sectional surveys (1997 and 2002).
Total number of IVF, ICSI and FET treatments initiated more than tripled between 1992 and 2004. The proportion of tubal injury as a cause of infertility treatment decreased over time while other female factors, male factor and multiple causes became more common. Self-reported lifetime subfertility was 16.0% in 2002 among women aged 25-64 years. Subfertility differed notably by age and education: young less educated women and older more educated women more frequently reported subfertility. Use of hormone therapy to treat subfertility (1997 and 2002) and participation in infertility treatments or medical examinations (2002) was more common among urban, highly educated and affluent women.
The use of infertility treatments increased and the proportions of causes of infertility have changed over time. Self-reported subfertility differed by age and education. There are socio-demographic differences in the use of infertility treatments.
研究不孕治疗的使用情况随时间的变化、不孕原因、亚生育力的终生患病率以及社会人口学因素对不孕治疗使用情况的影响。
汇总1992 - 2004年的体外受精(IVF)统计数据以及两项具有全国代表性的横断面调查(1997年和2002年)的数据。
1992年至2004年间,开始进行的IVF、卵胞浆内单精子注射(ICSI)和冻融胚胎移植(FET)治疗总数增加了两倍多。输卵管损伤作为不孕治疗原因的比例随时间下降,而其他女性因素、男性因素和多种原因则变得更为常见。2002年,25 - 64岁女性自我报告的终生亚生育力为16.0%。亚生育力在年龄和教育程度上存在显著差异:年轻且受教育程度较低的女性以及年长且受教育程度较高的女性更频繁地报告亚生育力。在城市、高学历和富裕女性中,使用激素疗法治疗亚生育力(1997年和2002年)以及参与不孕治疗或医学检查(2002年)更为常见。
不孕治疗的使用增加,不孕原因的比例随时间发生了变化。自我报告的亚生育力在年龄和教育程度上存在差异。不孕治疗的使用存在社会人口学差异。