Montana Giovanni, Hoggart Clive
Imperial College London, Department of Mathematics, South Kensington Campus, 180 Queen's Gate, London SW7 2AZ.
Brief Bioinform. 2007 Nov;8(6):393-5. doi: 10.1093/bib/bbm035. Epub 2007 Jul 18.
Admixture mapping is a statistical methodology that detects genetic variants in recently admixed populations that are responsible for ethnic differences in disease risk. Three software packages are now available for admixture mapping and we provide a brief overview of the statistical methods and other principal features they implement.
混合映射是一种统计方法,用于在最近混合的人群中检测导致疾病风险存在种族差异的基因变异。目前有三个软件包可用于混合映射,我们将简要概述它们所采用的统计方法和其他主要特征。