慢性睾丸疼痛：在考虑手术之前，可先考虑使用加巴喷丁或去甲替林。
Chronic orchialgia: consider gabapentin or nortriptyline before considering surgery.
作者信息
Sinclair Andrew M, Miller Barry, Lee Ling K
机构信息
Department of Urological Surgery, Royal Bolton Hospital, Minerva Road, Farnworth, Bolton, UK.
出版信息
Int J Urol. 2007 Jul;14(7):622-5. doi: 10.1111/j.1442-2042.2007.01745.x.
OBJECTIVE
To establish if there is a role for gabapentin or nortriptyline in the treatment of chronic orchialgia.
METHODS
Twenty-six consecutive patients with chronic orchialgia were seen in the chronic pain clinic by a multidisciplinary team. A pain questionnaire was completed prior to commencing either gabapentin or nortriptyline. They were reviewed at 3 months and a repeat questionnaire completed. A 50% improvement in pain was considered successful.
RESULTS
Complete data was available for 19 patients. Overall, 61.5% of patients commenced on gabapentin and 66.6% of patients commenced on nortriptyline had a greater than 50% improvement in pain. Patients with post-vasectomy testicular pain were considered as a subgroup. None of these patients had a greater than 50% improvement in pain. However, 80% of patients in the subgroup with idiopathic chronic orchialgia had a greater than 50% improvement in pain.
CONCLUSION
Although this is a small study, it appears that gabapentin and nortriptyline are effective in the treatment of idiopathic chronic orchialgia but not post-vasectomy pain.
目的
确定加巴喷丁或去甲替林在慢性睾丸痛治疗中是否起作用。
方法
多学科团队在慢性疼痛门诊诊治了26例连续的慢性睾丸痛患者。在开始使用加巴喷丁或去甲替林之前完成一份疼痛问卷。3个月时进行复查并完成一份重复问卷。疼痛改善50%被视为治疗成功。
结果
19例患者有完整数据。总体而言，开始使用加巴喷丁的患者中有61.5%、开始使用去甲替林的患者中有66.6%疼痛改善超过50%。输精管切除术后睾丸疼痛患者被视为一个亚组。这些患者中无一例疼痛改善超过50%。然而，特发性慢性睾丸痛亚组中80%的患者疼痛改善超过50%。
结论
尽管这是一项小型研究，但加巴喷丁和去甲替林似乎对特发性慢性睾丸痛有效，对输精管切除术后疼痛无效。
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