Shrivastava Vikas, Christensen Rebecca, Poggi Matthew M
Division of Radiation Oncology, National Naval Medical Center, Bethesda, MD 20889, USA.
Clin Genitourin Cancer. 2007 Jun;5(5):341-3. doi: 10.3816/CGC.2007.n.015.
A 58-year-old white man with prostate-specific antigen (PSA) level of 6 ng/mL, a Gleason score of 6 (3+3), and T2a adenocarcinoma of the prostate underwent prostatectomy. On review of the pathology, the specimen contained a Gleason score of 8 (3+5) with other high-risk features. The patient had a persistently elevated postoperative PSA level and was placed on total androgen blockade. The PSA continued to increase, and the patient developed bone-only metastatic disease. The patient was treated with palliative external-beam radiation and samarium. Six months later, he presented with bilateral hearing loss and was found to have pathologic and radiographic evidence of metastatic prostate cancer to the external auditory canals. This was an unusual late finding. The patient died shortly afterward before completing palliative treatment to the area.
一名58岁的白人男性，前列腺特异性抗原（PSA）水平为6 ng/mL，Gleason评分6分（3+3），患有前列腺T2a期腺癌，接受了前列腺切除术。病理检查显示，标本的Gleason评分为8分（3+5），伴有其他高危特征。患者术后PSA水平持续升高，遂接受全雄激素阻断治疗。PSA继续升高，患者出现仅骨转移的疾病。患者接受了姑息性外照射放疗和钐治疗。六个月后，他出现双侧听力丧失，经检查发现有病理及影像学证据表明前列腺癌转移至外耳道。这是一个不寻常的晚期发现。患者不久后在完成该区域的姑息治疗前死亡。
