Niimi Yasunari, Song Joon K, Berenstein Alejandro
Center for Endovascular Surgery, Institute for Neurology and Neurosurgery, Roosevelt Hospital, 1000 Tenth Avenue, New York, NY 10019, USA.
Neuroimaging Clin N Am. 2007 May;17(2):223-37. doi: 10.1016/j.nic.2007.02.002.
Maxillofacial vascular malformations (MFVMs) are formed due to an error of vascular morphogenesis. They generally grow in proportion to the growth of the affected child but may increase in size secondary to various triggering factors such as increased blood flow, arterial occlusion, and venous thrombosis. The development of an individual lesion, especially if it is high flow, may be stimulated by various factors. High flow in an existing MFVM can induce arteriovenous shunting, which, in turn, increases flow demand, cascading enlargement of the malformation. Increased understanding of these additional physiologic variants may help to define their clinical presentation and evolution and assist in designing therapeutic strategies.
颌面血管畸形（MFVMs）是由于血管形态发生错误而形成的。它们通常与患病儿童的生长成比例生长，但可能因各种触发因素（如血流量增加、动脉闭塞和静脉血栓形成）而增大。单个病变的发展，尤其是高流量病变，可能受到多种因素的刺激。现有MFVM中的高流量可诱发动静脉分流，进而增加流量需求，导致畸形连锁性增大。对这些额外生理变异的进一步了解可能有助于明确其临床表现和演变，并有助于设计治疗策略。
