儿童脑静脉窦血栓形成

Cerebral sinovenous thrombosis in children.

作者信息

Jonas Kimchi Tali, Lee Seon Kyu, Agid Ronit, Shroff Manohar, Ter Brugge Karel G

机构信息

Division of Neuroradiology, Toronto Western Hospital, Department of Medical Imaging, University Health Network (UHN), University of Toronto, Toronto, Ontario, Canada.

出版信息

Neuroimaging Clin N Am. 2007 May;17(2):239-44. doi: 10.1016/j.nic.2007.01.006.

DOI:10.1016/j.nic.2007.01.006

PMID:17645973

Abstract

Sinovenous thrombosis in children is rare, and the symptoms and signs are nonspecific especially in the neonatal population. MR imaging seems to be the most sensitive for accurate diagnosis of dural sinus thrombosis. General medical and neurologic supportive care is the mainstay of treatment. However, more active medical treatment such as anticoagulation, as well as an aggressive form of treatment such as retrograde transvenous fibrinolytic therapy, in children whose condition declines despite adequate anticoagulation therapy can be justified.

摘要

儿童静脉窦血栓形成较为罕见，其症状和体征缺乏特异性，在新生儿群体中尤为如此。磁共振成像（MR）似乎是准确诊断硬脑膜窦血栓形成最敏感的方法。一般的医学和神经支持治疗是主要的治疗手段。然而，对于尽管接受了充分的抗凝治疗但病情仍恶化的儿童，采取更积极的药物治疗如抗凝，以及诸如逆行静脉内溶栓治疗等积极的治疗方式是合理的。