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智力功能对自闭症谱系障碍核心症状范围的影响。

The effects of intellectual functioning on the range of core symptoms of autism spectrum disorders.

作者信息

Matson Johnny L, Dempsey Timothy, Lovullo Santino V, Wilkins Jonathan

机构信息

Department of Psychology, Louisiana State University, Baton Rouge, LA 70803, USA.

出版信息

Res Dev Disabil. 2008 Jul-Aug;29(4):341-50. doi: 10.1016/j.ridd.2007.06.006. Epub 2007 Jul 23.

Abstract

Autism spectrum disorders (ASD) are a class of conditions categorized by communication problems, ritualistic behaviors, and inappropriate social behaviors. While there is much evidence to support a genetic link for ASD, an identified genetic marker remains elusive. As such, practitioners place considerable emphasis on traditional measures of intelligence and adaptive behavior to aid in diagnosis. Despite the fact that these measures are commonplace, little research has been conducted to shed light on whether deficits in intellectual functioning affect the range of core symptoms for ASD. This study represents a first attempt to determine whether level of IQ has an effect on the expression of ASD symptoms in adults with intellectual disability (ID). Three hundred and six adults, 151 with both ASD and ID and 155 with ID alone, were evaluated with respect to the nature and extent of their ASD symptoms and intellectual functioning. Individuals with autism displayed a higher number of symptoms than those with pervasive developmental disorder-not otherwise specified (PDD-NOS) on all three domains of impairment (social, communication, repetitive behaviors). As expected, persons with ID alone evinced far fewer symptoms than both these groups. IQ level was found to be a moderator for expression of ASD symptoms for the entire sample but not for the autism group.

摘要

自闭症谱系障碍(ASD)是一类以沟通问题、仪式化行为和不适当社交行为为特征的病症。虽然有大量证据支持ASD存在遗传联系,但尚未找到明确的遗传标记。因此,从业者非常重视传统的智力和适应性行为测量方法以辅助诊断。尽管这些测量方法很常见,但很少有研究探讨智力功能缺陷是否会影响ASD的核心症状范围。本研究首次尝试确定智商水平是否会对成年智力残疾(ID)患者的ASD症状表现产生影响。对306名成年人进行了评估,其中151名患有ASD和ID,155名仅患有ID,评估内容包括他们的ASD症状性质和程度以及智力功能。在所有三个损害领域(社交、沟通、重复行为)中,自闭症患者表现出的症状数量均高于未另行指明的广泛性发育障碍(PDD-NOS)患者。正如预期的那样,仅患有ID的人表现出的症状远少于这两组。研究发现,智商水平是整个样本中ASD症状表现的调节因素,但对自闭症组则不是。

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