Zabel R W, MacDonald I M, Mintsioulis G
Department of Ophthalmology, Ottawa Civic Hospital, ON.
Can J Ophthalmol. 1991 Dec;26(7):367-73.
Focal corneal edema overlying the site of argon laser iridotomy followed by generalized corneal decompensation developed in six eyes of five patients. The average interval between the iridotomy and the development of focal edema was 3 years, with generalized edema appearing an average of 3.5 months later. Light, scanning and transmission electron microscopy of tissue removed at the time of corneal transplantation showed abnormalities characteristic of Fuchs' dystrophy in two patients. Possible contributing factors include episodes of intraocular pressure elevation, cornea guttata and the use of high total amounts of energy during laser iridotomy.
5例患者的6只眼睛在氩激光虹膜切开术部位出现局限性角膜水肿，随后发生广泛性角膜失代偿。虹膜切开术与局限性水肿出现之间的平均间隔为3年，广泛性水肿平均在3.5个月后出现。角膜移植时切除的组织进行光镜、扫描电镜和透射电镜检查显示，2例患者具有富克斯角膜内皮营养不良的特征性异常。可能的促成因素包括眼压升高、角膜小滴以及激光虹膜切开术期间使用的总能量过高。
