Köhler B, Persson M
Department of Cariology, University of Göteborg, Gothenburg, Sweden.
Community Dent Oral Epidemiol. 1991 Dec;19(6):352-6. doi: 10.1111/j.1600-0528.1991.tb00186.x.
The number of Streptococcus mutans, Streptococcus sobrinus, and lactobacilli in whole stimulated saliva was examined in 130 dentate 80- and 85-yr-old persons. 88.5% were positive for mutans streptococci and 29% carried greater than 10(6) cfu per ml saliva. S. mutans was most frequently isolated and was found in 114 persons (88%) alone or in combination with S. sobrinus. S. sobrinus was detected in 33 persons (25%), who also showed significantly higher salivary numbers of both mutans streptococci and lactobacilli than persons from whom S. sobrinus was not isolated. The S. sobrinus carriers also had significantly lower stimulated saliva secretion rates than the non-carriers. 95% of the subjects had detectable levels of lactobacilli in saliva with 35% having greater than 10(5) cfu per ml saliva. When the subjects were divided into classes according to the number of intermaxillary contacts, i.e. the Eichner classification, the distribution of subjects with high and low salivary counts of cariogenic bacteria varied. Thus fewer subjects belonging to Eichner class A showed higher salivary numbers of mutans streptococci (14% had greater than 10(6) cfu/ml) as well as lactobacilli (21% had greater than 10(5) cfu/ml) than, for example, subjects belonging to Eichner class B (26% had greater than 10(6) cfu/ml of mutans streptococci, 35% had greater than 10(5) cfu/ml of lactobacilli). Subjects who carried a removable denture(s) had significantly higher salivary numbers of both mutans streptococci and lactobacilli than subjects without removable dentures.
对130名80岁和85岁有牙的老人全刺激唾液中的变形链球菌、远缘链球菌和乳酸杆菌数量进行了检测。88.5%的人变形链球菌呈阳性，29%的人每毫升唾液中变形链球菌的菌落形成单位（cfu）大于10⁶。变形链球菌最常被分离出来，在114人（88%）中单独发现或与远缘链球菌一起发现。在33人（25%）中检测到远缘链球菌，这些人唾液中的变形链球菌和乳酸杆菌数量也明显高于未分离出远缘链球菌的人。远缘链球菌携带者的刺激唾液分泌率也明显低于非携带者。95%的受试者唾液中可检测到乳酸杆菌水平，35%的人每毫升唾液中乳酸杆菌大于10⁵ cfu。当根据颌间接触数量将受试者分为不同类别时，即艾希纳分类法，致龋菌唾液计数高和低的受试者分布有所不同。因此，与例如艾希纳B类受试者相比，属于艾希纳A类的受试者唾液中变形链球菌数量较高（14%大于10⁶ cfu/ml）以及乳酸杆菌数量较高（21%大于10⁵ cfu/ml）的人数较少（26%的人变形链球菌大于10⁶ cfu/ml，35%的人乳酸杆菌大于10⁵ cfu/ml）。佩戴可摘义齿的受试者唾液中的变形链球菌和乳酸杆菌数量均明显高于未佩戴可摘义齿的受试者。
